高效液相色谱-串联质谱法测定水中的六溴环十二烷和四溴双酚A  

Determination of hexabromocyclododecanes and tetrabromobisphenol a in water by high performance liquid chromatography-tandem mass spectrometry

作　　者：朱超飞[1] 郭靖[1] 杨文龙[1] 殷也筑 杨茜 范红利 吕美玲[2] 杜兵[1] ZHU Chaofei;GUO Jing;YANG Wenlong;YIN Yezhu;YANG Xi;FAN Hongli;LYU Meiling;DU Bing(State Environmental Protection Key Laboratory of Dioxin Pollution Control,National Research Center for Environmental Analysis and Measurement,Beijing,100029,China;Agilent Technologies(China)Ltd.,Inc.,Beijing,100102,China)

机构地区：[1]国家环境保护二噁英污染控制重点实验室,国家环境分析测试中心,生态环境部环境发展中心,北京100029 [2]安捷伦科技(中国)有限公司,北京100102

出　　处：《环境化学》2022年第9期3121-3124,共4页Environmental Chemistry

基　　金：典型水体新污染物筛查、溯源和监测技术研究及应用示范”项目(JSZC-G2021-291)资助。

摘　　要：本文建立了同时测定水中六溴环十二烷(HBCDs)和四溴双酚A(TBBPA)的高效液相色谱-串联质谱方法.酸化后的水样(pH=2—4)经二氯甲烷液液萃取,硅胶固相萃取小柱净化后,经LC-MS/MS检测,采用同位素稀释法进行定量.目标化合物的方法检出限在0.3—0.5 ng·L^(−1)之间,不同水质样品平行添加的回收率为91.8%—117%,相对标准偏差是3.1%—11.9%.该方法灵敏度高、可靠性强,能够适用于环境各类水体中痕量HBCDs和TBBPA的监测要求.A method for simultaneous determination of hexabromocyclododecanes(HBCDs)and tetrabromobisphenol A(TBBPA)in waters was developed using LC-MS/MS.After being adjusted to pH=2—4,the water sample was subjected to liquid–liquid extraction using dichloromethane,and the extractant was then cleaned up by silica gel solid phase extraction(SPE)cartridge.The resultant sample was analyzed using LC-MS/MS and quantified by isotope dilution method.The limits of detection were in the range of 0.3—0.5 ng·L^(−1),and spiking recoveries ranged from 91.8%to 117%,with relative standard deviations of 3.1%—11.9%.The established method was reliable,sensitive and was suitable for the determination of HBCDs and TBBPA in various types of water matrixes.

关 键 词：六溴环十二烷 四溴双酚A 液相色谱-串联质谱法 水体 

分 类 号：O657.63[理学—分析化学] X832[理学—化学]