基于“阴不足”探讨糖皮质激素性骨质疏松的病机与证治  

Exploring the Pathogenesis and Treatment of Glucocorticoid Osteoporosis based on“Yin Deficiency”

作　　者：姜瑞 谭爱华 石和元[1] 张征[3] JIANG Rui;TAN Aihua;SHI Heyuan;ZHANG Zheng(Hubei University of Chinese Medicine,Hubei Wuhan 430065,China;Beijing University of Chinese Medicine,Beijing 100007,China;Huanggang Hospital of Traditional Chinese Medicine Affiliated of Hubei University of Chinese Medicine,Hubei Huanggang 438000,China)

机构地区：[1]湖北中医药大学,湖北武汉430065 [2]北京中医药大学博士后流动站,北京100007 [3]湖北中医药大学附属黄冈市中医医院,湖北黄冈438000

出　　处：《中医药临床杂志》2022年第8期1414-1417,共4页Clinical Journal of Traditional Chinese Medicine

基　　金：全国第六批名老中医药专家学术经验继承工作项目(国中医药人教发[2017]29号)。

摘　　要：目前糖皮质激素广泛应用于临床,疗效显著,但与此同时糖皮质激素也带来了很多不良反应,糖皮质激素性骨质疏松是其常见的副作用之一。由于人体具有“阴不足”的特点,肾阴难成易亏,当长期使用外源性的糖皮质激素后,导致肾阴亏虚,骨髓由于缺乏肾阴的充养,而髓减骨枯,发为骨痿,即骨质疏松症。该文基于“阴不足”的理论,探讨了糖皮质激素性骨质疏松各阶段的病机与证治,作者认为“阴不足”是该病的关键病机,在治疗时,无论该病处于哪一阶段,均应注重固护肾阴。At present,glucocorticoids are widely used in clinical practice with remarkable curative effect,but at the same time,glucocorticoids also bring many adverse reactions.Glucocorticoid-induced osteoporosis is one of its common side effects.Because the human body has the characteristics of“insufficiency of yin”,kidney yin is difficult to become and easy to lose.When exogenous glucocorticoid is used for a long time,it will lead to deficiency of kidney yin.Due to the lack of nourishment of kidney yin,the bone marrow is depleted and the bone is depleted,resulting in the development of kidney yin deficiency.For bone atrophy,that is,osteoporosis.Based on the theory of“Yin deficiency”,this paper discusses the pathogenesis,syndrome and treatment of glucocorticoid-induced osteoporosis in various stages.The author believes that“Yin deficiency”is the key pathogenesis of the disease.At any stage,attention should be paid to strengthening and protecting kidney Yin.

关 键 词：阴不足 糖皮质性骨质疏松 

分 类 号：R274[医药卫生—中医骨伤科学]