放射性^(131)I对老年甲亢患者的疗效分析  

Efficacy Analysis of Radioactive ^(131)I in Elderly Patients with Hyperthyroidism

作　　者：李道陵 Li Dao-ling(The Central Hospital of Yongzhou,Yongzhou 425000,Hunan Province,China)

机构地区：[1]永州市中心医院,湖南永州425000

出　　处：《中国社区医师》2022年第26期19-21,共3页Chinese Community Doctors

摘　　要：目的:研究老年甲亢患者接受放射性^(131)I治疗后的效果。方法:选取2018年1月-2020年5月永州市中心医院收治的60例老年甲亢患者作为研究对象,采用双盲法分为对照组和观察组,各30例。对照组采用他巴唑治疗,观察组采用放射性^(131)I治疗,观察两组患者治疗效果、甲减发生率、相关症状评分、患者满意指数及甲亢复发率。结果:观察组治疗总有效率高于对照组,差异有统计学意义(P<0.05);观察组甲减发生率低于对照组,差异有统计学意义(P<0.05);观察组大便频繁、心动过速、体重下降评分均低于对照组,差异有统计学意义(P<0.05);观察组疗程满意指数、预后情况满意指数及不良反应满意指数均高于对照组,差异有统计学意义(P<0.05);观察组半年复发率及1年复发率均低于对照组,差异有统计学意义(P<0.05)。结论:老年甲亢患者接受放射性I治疗,能够有效改善甲亢症状,降低甲减发生率及甲亢复发率,提高患者满意度。Objective: To study the effect of radioactive ^(131)I treatment in elderly patients with hyperthyroidism. Methods: Sixty elderly patients with hyperthyroidism treated in the Central Hospital of Yongzhou from January 2018 to May 2020 were selected as the study subjects. They were divided into control group and observation group by double-blinding method, with 30 cases in each group. The control group was treated with tapazole, and the observation group was treated with radioactive ^(131)I. The treatment effect,incidence of hypothyroidism, related symptom scores, patient’s satisfaction index and recurrence rate of hyperthyroidism were observed in the two groups. Results: The total effective rate of treatment in the observation group was higher than that in the control group, and the difference was statistically significant(P<0.05);the incidence of hypothyroidism in the observation group was lower than that in the control group, and the difference was statistically significant(P<0.05);the scores of frequent defecation,tachycardia and weight loss in the observation group were lower than those in the control group, and the difference was statistically significant(P<0.05);the treatment course satisfaction index, prognosis satisfaction index and adverse reaction satisfaction index of the observation group were higher than those of the control group, and the difference was statistically significant(P<0.05);the halfyear recurrence rate and one-year recurrence rate of the observation group were lower than those of the control group, and the difference was statistically significant(P<0.05). Conclusion: RadioactiveI therapy in elderly patients with hyperthyroidism can effectively improve the symptoms of hyperthyroidism, reduce the incidence of hypothyroidism and recurrence of hyperthyroidism,and improve patient’s satisfaction.

关 键 词：放射性^(131)I治疗 他巴唑 老年甲亢 

分 类 号：R581.1[医药卫生—内分泌]