基于“肺与大肠相表里”理论探讨益气健脾通便方治疗慢传输型便秘的疗效观察  

Clinical Effect of Yiqi Jianpi Tongbian Recipe Combined with Catgut Implantation at Acupoints on Slow Transit Constipation Based on the Theory of“Lung and Large Intestine are Interior-Exteriorly Related”

作　　者：张娟 王建民[3] ZHANG Juan;WANG Jianmin(The Third Affiliated Hospital of Anhui University of Medicine,Hefei 230001,Anhui,China;Hefei First People's Hospital,Hefei 230001,Anhui,China;The First Affiliated Hospital of Anhui University of Chinese Medicine,Hefei 230031,Anhui,China)

机构地区：[1]安徽医科大学第三附属医院,安徽合肥230001 [2]合肥市第一人民医院,安徽合肥230001 [3]安徽中医药大学第一附属医院,安徽合肥230031

出　　处：《辽宁中医杂志》2022年第8期73-76,共4页Liaoning Journal of Traditional Chinese Medicine

基　　金：“十三五”医疗卫生重点专科建设项目([2016]658号);全国名老中医药专家传承工作室建设项目(2016);安徽中医药大学自然科学研究基金(2018zryb61);安徽省科技攻关计划项目(1501041151);安徽省卫生计生委中医药科研计划项目(2016zy02);安徽省高校自然科学基金项目(KJ2016A396)。

摘　　要：目的基于“肺与大肠相表里”探讨益气健脾通便方治疗慢传输型便秘的治疗效果。方法筛选我院收治的86例慢传输型便秘患者随机分2组,各43例,对照组接受我院常规治疗,治疗组加用益气健脾通便方治疗,疗程均28天。观察两组中医症状积分及肠神经递质水平,比较2组临床疗效及结肠传输试验的各项。结果治疗后,两组中医症状积分、便秘相关生活质量量表(PAC-QOL)相关指标降低,与对照组相比,治疗组中医症状积分、便秘相关生活质量量表(PAC-QOL)相关指标较低(P<0.05);治疗后,两组P物质(SP)水平均上升,血管活性肠肽(VIP)及生长抑素(SS)水平降低,与与对照组相比,治疗组P物质(SP)水平较高,生长抑素(SS)水平较低(P<0.05);且与对照组相比,治疗组治疗48 h、72 h排便排出数及72 h排便排出率较高(P<0.05),治疗组的临床总有效率较高(P<0.05)。结论基于“肺与大肠相表里”理论,结合患者肺脾气虚的临床表现,从肺、脾、大肠三方面入手,运用益气健脾通便方治疗慢传输型便秘,在补脾气的同时补肺气,具有补益肺气、健脾补虚、通便行气、和胃消积之功,可改善患者排便困难、周身乏力、肢体倦怠、脘腹胀满等临床症状,加快肠道传输,调节肠神经递质水平,提高生活质量,以证实“肺肠同治”的合理性,疗效显著。Objective Clinical Effect of Yiqi Jianpi Tongbian Recipe Combined with Catgut Implantation at Acupoints on Slow Transit Constipation Based on the Theory of“Lung and Large Intestine are Interior-Exteriorly Related”.Methods A total of 86 patients with slow transit constipation in our hospital were selected and randomly divided into two groups(n=43).The control group received conventional treatment,and the study group was treated with Yiqi Jianpi Tongbian prescription,the course of treatment was 28 days.The scores of TCM symptoms and the changes of intestinal neurotransmitter levels were observed between the two groups,and the colon transmission test indexes and clinical efficacy were compared between the two groups.Results After treatment,the TCM symptom score and the relevant indicators of the constipation related quality of life scale(pac-qol)in the two groups decreased.Compared with the control group,the TCM symptom score and the relevant indicators of the constipation related quality of life scale(pac-qol)in the study group were lower(P<0.05).After treatment,the levels of substance P(SP)increased,while the levels of vasoactive intestinal peptide(VIP)and somatostatin(SS)decreased in both groups.Compared with the control group,the levels of substance P(SP)and somatostatin(SS)in the study group were higher and lower(P<0.05).Compared with the control group,the number of feces excreted at 48h and 72h and the rate of feces excreted at 72h in the study group were higher(P<0.05),and the total clinical effective rate in the study group was higher(P<0.05).Conclusion Based on the theory of“lung and large intestine on the surface and in the interior”,combined with the clinical manifestations of lung qi deficiency in patients,from the three aspects of lung,spleen and large intestine,the prescription for supplementing qi and invigorating lung qi is applied to treat slow transmission constipation,which has the effect of supplementing qi,invigorating spleen and invigorating deficiency,relieving qi and eliminating accum

关 键 词：益气健脾通便方 慢传输型便秘 临床疗效 神经递质 

分 类 号：R256.35[医药卫生—中医内科学]