李可老中医“引火归原”法在功能性子宫出血中的临床应用研究  

Clinical Application of“Conducting The Fire Back to Its Origin”Method of Old TCM Physician LI Ke in Treatment of Functional Uterine Bleeding

作　　者：林锦韬[1] 李爱武[1] 刘钊汝[1] 宫凤英[1] 张强[1] 李永春[1] 黄荣铝[1] 吕英[1] 成云水[1] LIN Jintao;LI Aiwu;LIU Zhaoru;GONG Fengying;ZHANG Qiang;LI Yongchun;HUANG Ronglyu;LYU Ying;CHENG Yunshui(Department of Ancient Chinese Medicine,Southern Hospital,Southern Medical University,Guangzhou 510515,Guangdong,China)

机构地区：[1]南方医科大学南方医院古中医科,广东广州510515

出　　处：《辽宁中医杂志》2022年第8期129-132,共4页Liaoning Journal of Traditional Chinese Medicine

基　　金：广东省中医药局面上项目(20191224);2020年广东省中医药局面上项目(20201232);院长基金(2019B036,2020B031)。

摘　　要：目的探讨李可老中医“引火归原”法在功能性子宫出血中的临床疗效。方法回顾性分析2017年1—2019年8月该院接受治疗的60例功能性子宫出血患者临床资料,按照治疗方式不同分为观察组和对照组,各30例。对照组患者采用去氧孕烯炔雌醇片治疗,观察组在对照组基础上,联合“引火归原”法治疗,均持续治疗3个月经周期。比较两组治疗3个月月经周期后的临床疗效,并比较治疗前、治疗3个月经周期后子宫内膜厚度、中医证候积分、血清促卵泡生成素(LSH)、黄体生成素(LH)、雌二醇(E)水平的变化、停药后1年的复发率及治疗期间不良反应发生率。结果治疗后,观察组患者的临床疗效总有效率为93.33%(28/30),明显高于对照组的73.33%(22/30),差异有统计学意义(P<0.05);观察组患者子宫内膜厚度为(5.76±0.85)mm,明显低于对照组的(8.02±1.14)mm,差异有统计学意义(P<0.05);观察组患者淋漓不尽、经血黯淡、腰膝酸软证候积分分别为(2.15±0.35)分、(1.95±0.37)分、(1.48±0.27)分,均明显低于对照组的(2.88±0.41)分、(2.79±0.46)分、(2.01±0.33)分,差异有统计学意义(P<0.05);观察组患者血清LSH、LH、E水平分别为(20.34±3.57)U/L、(16.20±2.17)U/L、(162.03±28.41)pmol/L,均明显低于对照组的(27.41±3.22)U/L、(22.05±2.43)U/L、(213.42±33.53)pmol/L,差异有统计学意义(P<0.05);观察组患者停药后1年复发率为3.33%(1/30),明显低于对照组的20.00%(6/30),差异有统计学意义(P<0.05);两组用药期间均无明显不良反应。结论李可老中医“引火归原”法在功能性子宫出血患者中的临床疗效明显,可有效促进疾病恢复,值得推广应用。Objective To study the curative efficacy the“conducting the fire back to its origin”method of old TCM physician LI Ke in treatment of functional uterine bleeding.Methods The clinical data of 60 patients with functional uterine bleeding treated in the hospital from January 2017 to August 2019 was retrospectively analyzed.According to different treatment methods,they were divided into observation group and control group,30 cases in each group.The the control group’s patients were treated with desogestrel ethinylestradiol tablets,while the observation group’s patients were combined with the“conducting the fire back to its origin”method on the basis of the control group,and the treatment lasted for 3 menstrual cycles.The clinical efficacy of the two groups after 3 menstrual cycles was compared,and the endometrial thickness,TCM syndrome score,serum levels of follicle stimulating hormone(LSH),luteinin(LH)and estradiol(E)were compared before and after 3 menstrual cycles,the recurrence after drug discontinuation for 1 year and adverse reactions during the treatment were compared.Results After treatment,the total effective rate in the observation group was 93.33%(28/30),which was significantly higher than 73.33%(22/30)of the control group,and the difference was statistically significant(P<0.05).The endometrial thickness in the observation group was(5.76±0.85)mm,which was significantly lower than that[(8.02±1.14)mm]of the control group and the difference was statistically significant(P<0.05).The endless dripping,dull blood,waist and knee syndrome syndrome scores were(2.15±0.35)points,(1.95±0.37)points and(1.48±0.27)points,which were significantly lower than those of the control group[(2.88±0.41)points,(2.79±0.46)points,(2.01±0.33)points],and the difference were statistically significant(P<0.05).The serum levels of LSH,LH and Ein the observation group were(20.34±3.57)U/L,(16.20±2.17)U/L and(162.03±28.41)pmol/L,which were significantly lower than those of the control group[(27.41±3.22)U/L,(22.05±2.43

关 键 词：功能性子宫出血 李可 “引火归原”法 子宫内膜厚度 中医证候积分 性激素 疗效 

分 类 号：R711.74[医药卫生—妇产科学]