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作 者:谢蕊 黄运里[2] XIE Rui;HUANG Yunli(Anesthesiology Department,Xixia County People's Hospital,Nanyang 474500;Anesthesia and Perioperative Medicine Department,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450003,China)
机构地区:[1]西峡县人民医院麻醉科,河南南阳474500 [2]郑州大学第一附属医院麻醉与围术期医学部,河南郑州450003
出 处:《临床医学研究与实践》2022年第28期104-106,共3页Clinical Research and Practice
摘 要:目的 探究竖脊肌平面阻滞(ESPB)对腰椎手术患者镇痛及术后早期恢复的影响。方法 选取2017年1月至2021年1月我院收治的98例腰椎手术患者为研究对象,采用随机双盲对照试验将其分为对照组和观察组,各49例。对照组采用全身麻醉(GA),观察组采用GA+ESPB。比较两组的疼痛评分、苏醒质量评分、细胞因子水平及不良反应发生情况。结果 术后2、24、72 h,观察组的视觉模拟评分法(VAS)评分低于对照组(P<0.05)。拔管即刻、术后30 min、术后2 h,观察组的Steward苏醒评分高于对照组(P<0.05)。术后2 h,观察组的5-羟色胺(5-HT)、P物质(SP)、肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)水平低于对照组(P<0.05)。两组的不良反应总发生率无显著差异(P>0.05)。结论 ESPB用于腰椎手术患者中的效果显著,有利于提高镇痛效果,促进术后早期恢复。Objective To investigate the effect of erector spinae plane block(ESPB) on analgesia and early postoperative recovery in patients undergoing lumbar surgery. Methods A total of 98 patients with lumbar surgery admitted in our hospital from January 2017 to January 2021 were selected as the research objects. The patients were divided into control group and observation group by random double-blind controlled trial, with 49 cases in each group. The control group was treated with general anesthesia(GA), and the observation group was treated with GA + ESPB. The pain score, awakening quality score, cytokine levels and occurrence of adverse reactions were compared between the two groups.Results At 2, 24 and 72 h after operation, the Visual Analogue Scale(VAS) score of the observation group was lower than that of the control group(P<0.05). Immediately after extubation, 30 min after operation, 2 h after operation, the Steward awakening score of the observation group was higher than that of the control group(P<0.05). At 2 h after operation, the levels of 5-hydroxytryptamine(5-HT), substance P(SP), tumor necrosis factor-α(TNF-α) and interleukin-6(IL-6) in the observation group were lower than those in the control group(P <0.05). There was no significant diffetence in the total incidence of adverse reactions between the two groups(P>0.05). Conclusion ESPB has a significant effect on effective in patients undergoing lumbar surgery, which can improve the analgesic effect and promote early postoperative recovery.
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