MRI增强比联合ADC值在血管周细胞瘤与脑膜瘤鉴别诊断中的应用研究  

Application of Enhancement Ratios on Magnetic Resonance Imaging and Apparent Diffusion Coefficients in Differentiating Intracranial Hemangiopericytoma from Meningioma

作　　者：努尔阿丽牙·艾力 丁爽 Nueraliya.AILI;DING Shuang(Imaging Center of Kashgar Second People's Hospital,Kashgar 844000,China;Imaging Center of the First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China)

机构地区：[1]喀什地区第二人民医院影像中心,新疆喀什844000 [2]新疆医科大学第一附属医院影像中心,新疆乌鲁木齐830054

出　　处：《中国CT和MRI杂志》2022年第10期10-11,16,共3页Chinese Journal of CT and MRI

基　　金：新疆维吾尔自治区科技支撑项目(2020E0275)。

摘　　要：目的探讨经过常规MRI增强扫描获得的MRI增强比联合ADC值在鉴别颅内血管周细胞瘤与脑膜瘤中的应用价值;方法回顾性分析颅内血管周细胞瘤15例及脑膜瘤30例患者的MRI图像,根据肿瘤位置,每例血管周细胞瘤患者与两例脑膜瘤患者相匹配,先测量两类肿瘤实性部分及对侧正常脑白质的平均增强值及平均ADC值,再计算MRI增强比(即肿瘤组织平均增强值/对侧正常脑白质平均增强值)和标准化ADC值(即肿瘤组织平均ADC/对侧正常脑白质平均ADC),进行统计学分析;结果血管周细胞瘤的MRI增强比和ADC值均较脑瘤高(P<0.05);MRI增强比鉴别血管周细胞瘤与脑膜瘤的ROC曲线下面积为0.818,最佳诊断阈值为1.565,诊断灵敏度为100%,特异度为60%;平均ADC值鉴别血管周细胞瘤与脑膜瘤的ROC曲线下面积为0.8,最佳诊断阈值为0.115×10^(-3)m^(2)/s,诊断灵敏度为60%,特异度为100%。结论血管周细胞瘤的MRI增强比和ADC值均较脑膜瘤高(P<0.05),结合MRI增强比及ADC值测量可为血管周细胞瘤与脑膜瘤的鉴别诊断提供一定的参考价值。Objective Background and purpose To investigate the application value of enhancement ratios and apparent diffusion coefficients in differentiating intracranial hemangiopericytoma and meningioma.Methods MRI images of 15 cases of intracranial hemangiopericytoma and 30 cases of meningioma were retrospectively analyzed,each patient with hemangiopericytoma was matched with two meningioma patients based on tumour location.Mean enhancement value and mean apparent diffusion coefficients(ADC)were measured in the tumour and the contralateral normal-appearing white matter(NAWM).Enhancement ratio(ER)and anormalized ADC was calculated.Results Hemangiopericytoma had a higher ER and mean ADC compared to that of meningiomas(P<0.05),the area under ROC curve of ER for distinguishing hemangiopericytoma from meningioma was 0.818,the optimal diagnostic threshold was 1.565,the diagnostic sensitivity was 100%,the specificity was 60%;The area under ROC curve of ADC value for distinguishing hemangiopericytoma from meningioma was 0.8,the optimal diagnostic threshold was 0.115×10^(-3)m^(2)/s,the diagnostic sensitivity was 60%,the specificity was 100%.Conclusion Hemangiopericytomas showed significantly higher ER and ADC value compared to that of meningiomas,The combination of the two provides a certain reference value for the differential diagnosis of hemangiopericytoma and meningioma.

关 键 词：血管周细胞瘤 脑膜瘤 MRI增强比 表观扩散系数 

分 类 号：R445.2[医药卫生—影像医学与核医学]