能谱CT多参数定性分析在儿童胸腹部肿瘤性病变的应用价值  

Application Value of Multi-Parameter Qualitative Analysis of Spectral CT in Children with Thoracic and Abdominal Neoplastic Lesions

作　　者：郝明珠[1] 张晓凡 王芳[1] 刘畅[2] 张旭[1] 王志伟 朱凯[1] HAO Ming-zhu;ZHANG Xiao-fan;WANG Fang;LIU Chang;ZHANG Xu;WANG Zhi-wei;ZHU Kai(Department of Medical Imaging(CT/MR),Harbin Children's Hospital(The Sixth Affiliated Hospital of Harbin Medical University),Harbin 150000,Heilongjiang Province,China;Department of Pediatrics,Department of Medical Imaging(CT/MR),Harbin Children's Hospital(The Sixth Affiliated Hospital of Harbin Medical University),Harbin 150000,Heilongjiang Province,China)

机构地区：[1]哈尔滨市儿童医院(哈尔滨医科大学附属第六医院)医学影像科(CT/MR)医学影像科,黑龙江哈尔滨150000 [2]哈尔滨市儿童医院(哈尔滨医科大学附属第六医院)医学影像科(CT/MR)儿内科,黑龙江哈尔滨150000

出　　处：《中国CT和MRI杂志》2022年第10期136-138,共3页Chinese Journal of CT and MRI

基　　金：黑龙江省卫生健康委科研课题(2019-236)。

摘　　要：目的探讨Revolution宽体能谱CT的单能量成像、能谱曲线、基物质分离等GSI分析工具及定性分析在儿童胸腹部良恶性肿瘤病变中的应用价值。方法收集2018年至2022年间55例行能谱GSI-CT模式下胸腹部增强扫描的良恶性肿瘤病变患儿,运用GSI-CT图像结合GSI分析工具对良恶性肿瘤病变患儿的相关病灶的病理符合率,用计数资料以(%)表示。平扫、动脉期及静脉期的K值、动脉期及静脉期的CT40keV、动脉期及静脉期的ΔCT40keV、动脉期及静脉期的NIC、动脉期及静脉期的ΔIC采用独立样本t检验,以P<0.05时差异有统计学意义。结果55例胸腹部肿瘤性病变患儿,共发现病灶60处,运用GSI分析工具后发现的病灶诊断与病理结果相符为55处,符合率为91.6%。恶性病变与良性病变的平扫、动、静脉期的能谱曲线斜率K,动脉期及静脉期的病灶标准化碘浓度NIC,病灶净增碘浓度ΔIC,40keV的ΔCT值之间存在差异,具有统计学意义;恶性肿瘤的能谱参数均高于良性肿瘤病变(P<0.05),差异具有统计学意义。结论能谱CT多参数成像技术及多重定量分析工具的使用,为小儿肿瘤的诊治提供更丰富、更精准的影像信息,为肿瘤术前评估和治疗方案选择提供临床帮助。Objective To investigate the application value of single energy imaging,energy spectrum curve,base material separation and other GSI analysis tools of Revolution wide-body spectral CT and qualitative analysis in children with benign and malignant thoracic and abdominal tumors lesions.Methods From 2018 to 2022,55 children with benign and malignant tumors lesions who underwent enhanced chest and abdomen scanning under spectral GSI-CT mode were collected.The pathological coincidence rate of related lesions in children with benign and malignant tumors lesions was expressed as(%)by using GSI-CT images combined with GSI analysis tool.Independent sample t-test was used for the K values of plain scan,arterial phase and venous phase,CT40keV of venous phase and arterial phase,ΔCT40keV of venous phase and arterial phase,NIC of arterial phase and venous phase,ΔIC of arterial phase and venous phase,P<0.05 was considered statistically significant.Results A total of 60 lesions were found in 55 children with thoracic and abdominal neoplastic lesions,and 55 lesions were found to be consistent with pathological results by using GSI analysis tool,and the coincidence rate was 91.6%.There were differences in the slope K of the energy spectrum curve between benign lesions and malignant in plain scan,arteriovenous and arteriovenous phases,the standardized iodine concentration NIC of the lesions in arterial and venous phases,the net iodine increase concentrationΔIC of the lesions,and theΔCT value of 40keV.The spectral parameters of malignant tumors were higher than those of benign tumors and lesions(P<0.05),and the differences were statistically significant.Conclusion The use of spectral CT multi-parameter imaging technology and multiple quantitative analysis tools can provide richer and more accurate image information for the diagnosis and treatment of pediatric tumors,and provide clinical help for preoperative evaluation and treatment plan selection of tumors.

关 键 词：小儿 能谱CT 肿瘤 能谱曲线 单能量成像 

分 类 号：R445.3[医药卫生—影像医学与核医学]