2019—2021年广西流感监测结果分析  

Analysis of influenza surveillance in Guangxi from 2019 to 2021

作　　者：康宁[1] 陈华凤[1] 梁珍丽 王静[1] 张超 王晶[1] 闭福银[1] KANG Ning;CHEN Hua-feng;LIANG Zhen-li;WANG Jing;ZHANG Chao;WANG Jing;BI Fu-yin(Guangxi Center for Disease and Prevention,Nanning,Guangxi 530021,China)

机构地区：[1]广西壮族自治区疾病预防控制中心,广西南宁530028

出　　处：《现代预防医学》2022年第18期3440-3445,共6页Modern Preventive Medicine

基　　金：广西重点研发计划(桂科AB20149001);广西壮族自治区卫生健康委员会自筹经费科研课题(Z2015457、Z2016433)。

摘　　要：目的监测2019—2021年广西流感的流行情况,探索新冠疫情爆发前后广西流感的流行规律,为制定今后的流感和新冠防控方案提供科学依据。方法在广西的17家国家级哨点医院,每日统计流感样病例,对符合条件的流感样病例进行采样,对标本进行流感病毒及新冠病毒核酸检测,并对2019—2021年广西流感监测的病原学检测结果进行统计分析。结果广西流感监测网络在2019—2021年累计检测流感样病例标本69604份,流感病毒核酸阳性11619份,阳性率为16.69%,对流感病毒核酸阳性标本用MDCK细胞和鸡胚进行分离鉴定,共得到3641株毒株,其中甲型H1N1706株(19.39%),季节性甲型H3N2632株(17.36%),B型Victoria系2289株(62.87%),乙型Yamagata系14株(0.38%)。2020年4月开始对流感样病例同时进行的新冠病毒核酸检测结果均为阴性。结论2020年广西流感流行受到了新型冠状病毒肺炎疫情影响,从2、3月开始流感样病例数及流感病毒核酸检出阳性率显著降低,新冠预防措施有效控制了流感病毒的感染率。群体性的社会预防措施,即综合的非药物防控措施可以阻断流感和新冠等呼吸道传染病。Objective To monitor the epidemic of influenza in Guangxi from 2019 to 2021 and to explore the epidemic pattern of influenza in Guangxi before and after the outbreak COVID-19,so as to provide reference for the development of future influenza and COVID-19 prevention and control.Methods At 17 national sentinel hospitals in Guangxi,influenza-like cases were counted daily,eligible influenza-like cases were sampled,specimens were tested for influenza virus and nucleic acid of COVID-19,and the pathogenic detection results of influenza surveillance in Guangxi from 2019 to 2021 were statistically analyzed.Results From 2019 to 2021,the Guangxi influenza surveillance network detected a total of 69604 influenza-like case specimens and 11619 positive specimens,with a positive rate of 16.69%.In total 3641 strains were obtained by isolating and identifying influenza virus nucleic acid positive specimens with MDCK cells and chicken embryos,including 706 toxic virus strains influenza A(H1N1)virus,623 influenza A(H3N2),2289 influenza B(Votoria),and 14 influenza B(Yamagata).The SARS-CoV-2 nucleic acid tests of these samples were negative since April 2020.Conclusion The influenza epidemic in Guangxi in 2020 was affected by the COVID-19 epidemic,the number of influenza-like cases and the positive rate of influenza virus nucleic acid detection were significantly reduced from February and March,and the COVID-19 preventive measures effectively controlled the rate of influenza virus infection.Collective social preventive measures,i.e.,integrated non-pharmaceutical prevention and control measures,can interrupt respiratory infectious diseases such as influenza and COVID-19.

关 键 词：流感病毒 流感监测 新型冠状病毒肺炎 

分 类 号：R511.7[医药卫生—内科学] R181.8[医药卫生—临床医学]