广东省中老年人群睡眠状况与高血压患病的关联性研究  

Relationship between sleep status and hypertension in middle-aged and elderly people in Guangdong

作　　者：李爱娟 彭丹丹 王晔[2] 许晓君[2] 效拟 周少恩[2] 郑雪燕 李川 孟瑞琳[2] 刘茂玲 LI Ai-juan;PENG Dan-dan;WANG Ye;XU Xiao-jun;XIAO Ni;ZHOU Shao-en;ZHENG Xue-yan;LI Chuan;MENG Rui-lin;LIU Mao-ling(School of Public Health,Guangdong Pharmaceutical University,Guangzhou,Guangdong 510310,China;不详)

机构地区：[1]广东药科大学公共卫生学院,广东广州510310 [2]广东省疾病预防控制中心

出　　处：《现代预防医学》2022年第17期3228-3233,共6页Modern Preventive Medicine

摘　　要：目的研究广东省中老年人群睡眠状况与高血压患病的关联性,为高血压防控“关口前移”提供科学依据。方法采用“2018年广东省慢性病及危险因素监测数据”,按照多阶段整群随机抽样方法,纳入5636名≥45岁中老年人为研究对象。运用SAS 9.4软件进行Rao-ScottX~2检验和基于复杂抽样构建logistic回归模型分析睡眠状况与高血压患病的关系。运用R 4.0.5软件绘制限制性立方样条曲线分析睡眠时间与高血压患病风险的量效关系。结果广东省中老年人高血压患病率是37.93%,平均睡眠时间是(7.36±1.61)h;其中男性平均睡眠时间多于女性,而女性睡眠问题比例显著高于男性。经多因素回归模型控制后,睡眠时间不足或过多(OR=1.280,95%CI:1.128~1.452;OR=1.300,95%CI:1.038~1.627)、入睡困难(OR=1.286,95%CI:1.018~1.626)、中间觉醒≥2次(OR=1.239,95%CI:1.036~1.483)和服用安眠药(OR=1.567,95%CI:1.086~2.261)均使高血压患病风险升高。结论广东省中老年人群的睡眠时间不足或过多、入睡困难、中间觉醒≥2次和服用安眠药均与高血压患病显著正相关,应对该特征的人群进行干预,旨在降低高血压的患病率。Objective To study the correlation between sleep status and hypertension in the middle-aged and elderly population in Guangdong Province,and to provide scientific basis for hypertension prevention and control.Methods Data of chronic diseases risk factors surveillance in Guangdong Province in 2018 was analyzed.According to the multi-stage cluster random sampling method,5636 middle-aged and elderly people(≥45 years old)were included in the study.The Rao-Scottχ~2 test was performed with SAS 9.4 software and the relationship between sleep status and hypertension was analyzed by logistic regression model based on complex sampling.The dose-response relationship between sleep duration and hypertension was analyzed by drawing restricted cubic spline curve with R 4.0.5 software.Results The prevalence of hypertension was 37.93%and the average sleep time was(7.36±1.61)h.The average sleep time of males was more than that of females,and the proportion of females with sleep problems was significantly higher than that of males.After multi-factor regression model control,insufficient or excessive sleep time(OR=1.280,95%CI:1.128-1.452;OR=1.300,95%CI:1.038-1.627),difficulty in falling asleep(OR=1.286,95%CI:1.018-1.626),intermediate awakening≥2 times(OR=1.239,95%CI:1.036-1.483)and taking sleeping pills(OR=1.567,95%CI:1.086-2.261)were associated with increased risk of hypertension.Conclusion Insufficient or excessive sleep time,difficulty in falling asleep,≥2 awakenings and taking sleeping pills increase the risk of hypertension in the middle-aged and elderly population in Guangdong Province.Intervention should be carried out to reduce the prevalence of hypertension.

关 键 词：中老年人 睡眠状况 高血压 限制性立方样条 

分 类 号：R544.1[医药卫生—心血管疾病]