Artificial nanomotors: Fabrication, locomotion characterization, motion manipulation, and biomedical applications  

作　　者：Liangmeng Wang Xiaomeng Hao Zhixue Gao Zili Yang Yi Long Ming Luo Jianguo Guan 

机构地区：[1]State Key Laboratory of Advanced Technology for Materials Synthesis and Processing,International School of Materials Science and Engineering,Wuhan University of Technology,Wuhan,People's Republic of China [2]School of Materials Science&Engineering,Nanyang Technological University,Singapore,Singapore

出　　处：《Interdisciplinary Materials》2022年第2期256-280,共25页交叉学科材料（英文）

基　　金：This study was financially supported by the National Natural Science Foundation of China(22075222,21705123,and 51521001);the National Key R&D Program of China(2021YFA1201400).

摘　　要：Artificial nanomotors are nanoscale machines capable of converting surrounding other energy into mechanical motion and thus entering the tissues and cells of organisms.They hold great potential to revolutionize the diagnosis and treatment of diseases by actively targeting the lesion location,though there are many new challenges that arise with decreasing the size to nanoscale.This review sum-marizes and comments on the state-of-the-art artificial nanomotors with ad-vantages and limitations.It starts with the fabrication methods,including common physical vapor deposition and colloidal chemistry methods,followed by the locomotion characterization and motion manipulation.Then,the in vitro and in vivo biomedical applications are introduced in detail.The challenges and future prospects are discussed at the end.

关 键 词：biomedical application FABRICATION locomotion characterization motion manipulation NANOMOTOR 

分 类 号：TB383[一般工业技术—材料科学与工程] R318[医药卫生—生物医学工程]