超声引导下大隐静脉曲张介入硬化治疗的疗效与安全性分析  

Efficacy and safety of ultrasound-guided interventional sclerotherapy for varicosis of great saphenous vein

作　　者：张洪岗 闫敏 周富经 刘飞[2] Zhang Honggang;Yan Min;Zhou Fujing;Liu Fei(Department of Ultrasound,Fuyang Cancer Hospital,Fuyang 230000,Anhui,China;Department of General Surgery,Fuyang Cancer Hospital,Fuyang 230000,Anhui,China)

机构地区：[1]阜阳市肿瘤医院超声科,安徽阜阳230000 [2]阜阳市肿瘤医院普外科,安徽阜阳230000

出　　处：《血管与腔内血管外科杂志》2022年第8期1017-1021,共5页Journal of Vascular and Endovascular Surgery

摘　　要：目的探讨超声引导下大隐静脉曲张介入硬化治疗的远期疗效与安全性。方法收集2019年1月至2021年3月阜阳市肿瘤医院收治的87例大隐静脉曲张患者的临床资料,住院期间均接受超声引导下大隐静脉曲张介入硬化治疗,随访1~3年,收集患者的临床资料,包括人口学信息、病史资料、专科情况、随访结果,分析患者的治愈、复发情况。结果87例患者均在超声引导下一次性成功接受大隐静脉曲张介入硬化治疗,15例患者发生治疗相关并发症,12例患者于治疗后1个月行第2次超声引导大隐静脉曲张介入硬化治疗。随访结果显示,36例C5级患者末次随访溃疡面积为(2.3±0.7)cm^(2),明显低于治疗前的(4.8±1.1)cm^(2),差异有统计学意义(P<0.01);末次随访时11例C6级患者溃疡均愈合。治疗前,87例患者生活质量综合评定问卷-74(GQOL-74)评分为(203.7±4.2)分,明显低于末次随访的(239.4±4.8)分,差异有统计学意义(P<0.01)。87例患者均行彩色多普勒超声检查,均未发现深静脉血栓形成。结论超声引导下大隐静脉曲张介入硬化治疗具有较好的远期治疗效果和安全性,值得临床推广。Objective To investigate the long-term efficacy and safety of ultrasound-guided access to sclerotherapy for varicosis of great saphenous vein.Method The clinical data of 87 patients with varicosis of great saphenous vein admitted to Fuyang Cancer Hospital from January 2019 to March 2021 were collected.All subjects received ultrasoundguided sclerotherapy for varicosis of great saphenous vein access during hospitalization.Follow-up was carried out for 1 to 3 years,the clinical data of demographic information,medical history data,specialist conditions,and followup results were collected during the period.The cure and recurrence of the patients were analyzed.Result All 87 patients successfully received ultrasound-guided interventional sclerotherapy for varicosis of great saphenous vein at one time,15 patients developed complications related to the treatment,and 12 patients underwent a second ultrasoundguided interventional sclerosis for varicosis of great saphenous vein within one month after the treatment.The followup results showed that the ulcer area of 36 patients with C5 grade at the last follow-up was(2.3±0.7)cm^(2),which was significantly lower than that before the treatment whose value was(4.8±1.1)cm^(2),the difference was statistically significant(P<0.01).There were 11 cases with C6 grade at the last follow-up and their ulcers healed.Before treatment,the generic quality of life inventory-74(GQOL-74)score of 87 patients was(203.7±4.2)score,which was significantly lower than the last follow-up of(239.4±4.8)score,the difference was statistically significant(P<0.01).87 patients were examined by color Doppler ultrasound,and no deep vein thrombosis was found.Conclusion Ultrasound-guided interventional sclerotherapy for varicosis of great saphenous vein has a good long-term therapeutic effect and reliable safety,and is worthy of clinical promotion.

关 键 词：超声 大隐静脉曲张 硬化治疗 

分 类 号：R543[医药卫生—心血管疾病]