香槟方对腹腔镜全子宫切除术后胃肠动力作用的回顾性分析  

Effect of Xiangbin Prescription on Gastrointestinal Motility of Patients after Laparoscopic Panhysterectomy:A Retrospective Analysis

作　　者：吴宇燕 陈其城 蒋志 曹立幸[1,2] WU Yu-Yan;CHEN Qi-Cheng;JIANG Zhi;CAO Li-Xing(The Second Clinical Medical School of Guangzhou University of Chinese Medicine,Guangzhou 510405 Guangdong,China;The Second Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510120 Guangdong,China)

机构地区：[1]广州中医药大学第二临床医学院,广东广州510405 [2]广州中医药大学第二附属医院,广东广州510120

出　　处：《广州中医药大学学报》2022年第10期2262-2267,共6页Journal of Guangzhou University of Traditional Chinese Medicine

基　　金：国家区域中医(专科)诊疗中心建设专项资金资助项目(国中医药医政函[2018]205号);广东省哲学社会科学规划项目(编号:GD20LMZTS05);广东省基础与应用基础研究基金项目(编号:2021A151511077);广东省中医药局中医国家湿证重点实验室建设专项(编号:20225012);广东省中医院临床研究专项(编号:YN10101902);广东省中医院中医药科学技术研究专项(编号:YN2021MS01);广州中医药历史文化研究基地项目(编号:Y202103);广州中医药大学“双一流”与高水平大学学科协同创新团队项目(编号:2021xk48)。

摘　　要：【目的】观察香槟方对妇科腹腔镜全子宫切除术后患者胃肠动力的作用及安全性。【方法】采用回顾性分析方法,收集腹腔镜全子宫切除术后患者166例,根据围手术期有无使用香槟方将患者分为治疗组82例和对照组84例,分析2组患者术后胃肠功能恢复情况和安全性。【结果】(1)术后胃肠功能情况:(1)术后首次排气、排便时间和肠鸣音恢复正常时间:治疗组分别为(24.76±6.51)、(41.26±11.67)和(31.59±11.52)h,对照组分别为(27.20±8.52)、(47.79±13.88)和(37.37±16.43)h,组间比较,治疗组术后首次排气、排便时间和肠鸣音恢复正常时间均较对照组显著提前,差异均有统计学意义(P<0.05或P<0.01);(2)治疗组术后48 h内排气、排便和肠鸣音恢复正常的患者数量较对照组增多,其中术后48 h内排便和肠鸣音恢复正常的患者数量比较,差异均有统计学意义(P<0.01)。(3)术后延迟性胃肠运动抑制(PPOI)发生率:治疗组无PPOI发生,对照组PPOI发生率为1.19%,组间比较,差异无统计学意义(P>0.05)。(4)分层分析:对于年龄≤45岁、手术时间<180 min的患者,治疗组的术后胃肠功能恢复均较对照组快,差异均有统计学意义(P<0.05或P<0.01)。(2)安全性评价:研究过程中,2组患者均未出现不良反应,且患者的血常规、尿常规、肝肾功能及心电图等安全性指标均未见异常改变。【结论】中药香槟方可促进腹腔镜全子宫切除术后患者提前排气、排便,促进术后胃肠动力早期快速康复,且安全性好,值得临床推广使用。Objective To observe the effect and safety of Xiangbin Prescription on gastrointestinal motility of patients after laparoscopic panhysterectomy.Methods A retrospective analysis was conducted to collect 166 patients who underwent laparoscopic panhysterectomy.The patients were divided into the treatment group(82 cases)and the control group(84 cases)according to the use of Xiangbin Prescription or not after the operation.The control group was given postoperative fundamental treatment,and the treatment group was given oral use of Xiangbin Prescription(a proved prescription mainly composed of Radix Linderae,Fructus Amomi Villosi,Radix Ginseng,Semen Persicae and Semen Arecae)from the postoperative day one to the first defecation after surgery.The recovery of postoperative gastrointestinal function of the patients and the clinical safety of the two groups were analyzed.Results(1)Postoperative gastrointestinal function:(1)Time for first exhaust,time for first defecation,and time for the recovery of normal bowel sounds after the surgery in the treatment group were(24.76±6.51)hours,(41.26±11.67)hours and(31.59±11.52)hours respectively,and those in the control group were(27.20±8.52)hours,(47.79±13.88)hours and(37.37±16.43)hours,respectively.The intergroup comparison showed that the time for first exhaust,time for first defecation,and time for the recovery of normal bowel sounds after the surgery in the treatment group were significantly earlier than those in the control group,and the differences were statistically significant(P<0.05 or P<0.01).(2)The patients with exhaust,defecation and normal bowel sounds within 48-hour after surgery in the treatment group were more than those in the control group,and the differences of the amount of patients with defecation and normal bowel sounds within postoperative 48 hours between the two groups were statistically significant(P<0.01).(3)No prolonged postoperative ileus(PPOI)occurred in the treatment group while the incidence of PPOI in the control group was 1.19%.The intergroup

关 键 词：香槟方 全子宫切除术 胃肠功能 围手术期 回顾性分析 

分 类 号：R271.9[医药卫生—中西医结合]