氧驱雾化吸入普米克令舒治疗小儿哮喘急性发作的效果分析  

Effect analysis of oxygen-driven nebulization inhalation of Pulmicort Respules in the treatment of acute attack of asthma in children

作　　者：宋春玲 SONG Chun-ling(Liaoyang County Central Hospital,Liaoyang 111200,China)

机构地区：[1]辽阳县中心医院,111200

出　　处：《中国现代药物应用》2022年第17期116-118,共3页Chinese Journal of Modern Drug Application

摘　　要：目的分析氧驱雾化吸入吸入用布地奈德混悬液(商品名:普米克令舒)治疗小儿哮喘急性发作的临床效果。方法86例小儿哮喘急性发作患儿,根据治疗方式不同分为研究组和参照组,各43例。研究组患儿进行氧驱雾化吸入普米克令舒治疗,参照组患儿进行氧驱雾化吸入硫酸沙丁胺醇吸入气雾剂(商品名:万托林)治疗。比较两组患儿咳嗽、咳痰、肺部哮鸣音缓解时间及治疗效果、随访期间哮喘发作次数。结果研究组患儿咳嗽、咳痰及肺部哮鸣音缓解时间分别为(2.34±0.29)、(3.05±0.59)、(3.24±0.65)d,明显短于参照组的(3.98±0.71)、(4.42±0.90)、(5.32±1.42)d,差异具有统计学意义(P<0.05)。研究组患儿治疗总有效率93.02%高于参照组的76.74%,差异具有统计学意义(P<0.05)。研究组患儿随访期间哮喘发作次数为(1.25±0.24)次,少于参照组的(2.68±0.52)次,差异具有统计学意义(P<0.05)。结论小儿哮喘急性发作时选择氧驱雾化吸入普米克令舒治疗效果更佳,能够有效缩短症状缓解时间,减少哮喘发作次数,值得临床应用推广。Objective To analyze the clinical effect of oxygen-driven nebulization inhalation of budesonide suspension for inhalation(trade name:Pulmicort Respules)in the treatment of acute attack of asthma in children.Methods A total of 86 children with acute attack of asthma were divided into research group and reference group according to different treatment methods,with 43 cases in each group.The children in the research group were treated with oxygen-driven atomization inhalation of Pulmicort Respules,and the children in the control group were treated with oxygen-driven atomization inhalation of salbutamol sulfate inhalation aerosol(trade name:Ventolin).The remission time of cough,expectoration,pulmonary wheezing,therapeutic effect,and frequency of asthma attacks during the follow-up period were compared between the two groups.Results The remission time of cough,expectoration and pulmonary wheezing in the research group were(2.34±0.29),(3.05±0.59),and(3.24±0.65)d,which were significantly shorter than(3.98±0.71),(4.42±0.90),and(5.32±1.42)d in the reference group,and the differences were statistically significant(P<0.05).The total effective rate 93.02% in the research group was higher than 76.74%in the reference group,and the difference was statistically significant(P<0.05).During follow-up,the frequency of asthma attacks in the research group was(1.25±0.24)times,which was less than(2.68±0.52)times in the reference group,and the difference was statistically significant(P<0.05).Conclusion Oxygen-driven nebulization of Pulmicort Respules has good effect in the treatment of acute attack of asthma in children,and can effectively shorten the remission time of symptoms and reduce the frequency of asthma attacks,which is worthy of clinical application and promotion.

关 键 词：氧驱雾化 小儿哮喘 吸入用布地奈德混悬液 硫酸沙丁胺醇吸入气雾剂 

分 类 号：R725.6[医药卫生—儿科]