山鸡椒的化学成分、药理活性及临床应用研究进展  

Research progress on chemical constituents, pharmacological activities and clinical applications of Litsea cubeba

作　　者：陆玫霖 潘其明 王宝林 何宇铭 黄婉凤 陈明 钟国跃 杨世林[1,2] 高红伟 LU Mei-lin;PAN Qi-ming;WANG Bao-lin;HE Yu-ming;HUANG Wan-feng;CHEN Ming;ZHONG Guo-yue;YANG Shi-lin;GAO Hong-wei(College of Pharmacy,Guangxi University of Chinese Medicine,Nanning 530200,China;Jiangxi University of Traditional Chinese Medicine,Nanchang 330000,China)

机构地区：[1]广西中医药大学药学院,广西南宁530200 [2]江西中医药大学,江西南昌330000

出　　处：《中草药》2022年第17期5565-5581,共17页Chinese Traditional and Herbal Drugs

基　　金：广西中医药大学博士科研启动基金资助项目(2020BS017)。

摘　　要：山鸡椒Litsea cubeba在民间有着悠久的药用历史,可用于治疗腹痛吐泻、风湿痹痛、跌打损伤及脑血栓等疾病,主要含有挥发油类、生物碱类、木脂素类、黄酮类等化学成分,具有抗炎、抗肿瘤、抗菌、抗氧化、镇痛等药理作用。系统总结了1980—2021年国内外有关山鸡椒化学成分、药理活性及临床应用的研究进展,为其进一步开发和应用提供参考依据。Litsea cubeba has been historically used as a folk medicine to treat abdominalgia, vomiting and diarrhoea, rheumatic arthritis, traumatic injuries, and cerebral thrombosis. The plant mainly contains volatile oil, alkaloids, lignans, flavonoids and possesses a wide range of biological activities, such as anti-inflammatory, antitumor, antimicrobial, antitioxidant and analgesic activities.Research progress on chemical constituents, pharmacological activities and clinical applications of L. cubeba from 1980 to 2021 were reviewed in this paper, in order to provide a reference for further development and utilization of L. cubeba.

关 键 词：山鸡椒 挥发油 生物碱 木脂素 抗炎 祛风除湿 

分 类 号：R282.710.85[医药卫生—中药学]