2224例女性月经史及绝经年龄、绝经年限与骨质疏松症相关性研究  

A study on the relationship between menstrual history, menopausal age, menopausal years, and osteoporosis in 2224 women

作　　者：李建国 李鼎鹏 谢兴文 柴利军 丁聚贤 苏积亮 柳博 LI Jianguo;LI Dingpeng;XIE Xingwen;CHAI Lijun;DING Juxian;SU Jiliang;LIU Bo(The Affiliated Hospital of Northwest University for Nationalities,Lanzhou 730030,China;The Second People’s Hospital of Gansu Province,Lanzhou 730030,China)

机构地区：[1]西北民族大学附属医院,甘肃兰州730030 [2]甘肃省第二人民医院,甘肃兰州730030

出　　处：《中国骨质疏松杂志》2022年第9期1326-1329,共4页Chinese Journal of Osteoporosis

基　　金：国家自然科学基金(地区)(81860864,82160911);国家中医药管理局中医临床研究基地业务建设专项(JDZX2015080);甘肃省第二人民医院院内重点项目(YNZD2021-2);甘肃省中央引导地方科技发展专项(甘肃地区多发病防治能力提升创新平台)。

摘　　要：目的 分析兰州市两社区45岁以上女性初潮年龄、月经周期、月经天数及绝经年龄、绝经年限与骨质疏松症相关性。方法 采用现场问卷调查方式获取初潮年龄、月经周期、月经天数及绝经年龄、绝经年限等相关资料,应用双能X线骨密度检测仪测定骨密度。结果 (1)骨质疏松症患病率为32.73%,患病率随初潮年龄增加(P<0.01)及月经周期延长(P<0.05)而上升;患病率随月经天数增加而逐渐降低,但差异无统计学意义(P=0.104);(2)绝经后女性患病率(35.91%)显著高于未绝经女性(5.22%),组间差异存在统计学意义(P<0.01);不同绝经年龄与绝经年限组间差异存在统计学意义(P<0.01)。(3)单因素Logistic分析显示,初潮年龄、绝经史、绝经年龄、绝经年限与骨质疏松相关(P<0.05)。结论 兰州市两社区45岁以上女性骨质疏松症发生与初潮年龄、绝经史、绝经年龄、绝经年限相关,初潮年龄早、月经周期长、绝经年龄早、绝经年限长的绝经后女性应提早筛查、预防骨质疏松症的发生。Objective To analyze the relationship between age of menarche, menstrual cycle, menstrual days, menopausal age, duration of menopause and osteoporosis in women over 45 years old in the two communities in Lanzhou. Methods The data of age of menarche, menstrual cycle, menstrual days, and age and years of menopause were obtained by field questionnaire. Bone mineral density was measured using dual-energy X-ray densitometry. Results(1)The prevalence rate of osteoporosis was 32.73%, which increased with the increase of menarche age(P<0.01) and prolongation of menstrual cycle(P<0.05). The prevalence rate decreased with the increase of menstrual days, but there was no statistical significance(P=0.104).(2)The prevalence rate of postmenopausal women(35.91%) was significantly higher than that of premenopausal women(5.22%), and there was a significant difference between the groups(P<0.01). There were significant differences among different menopausal ages and years(P <0.01).(3)Univariate logistic analysis showed that age of menarche, history of menopause, age of menopause and years of menopause were correlated with osteoporosis(P<0.05). Conclusion The incidence of osteoporosis in women over 45 years old in the two communities in Lanzhou is related to age of menarche, history of menopause, age of menopause, and length of menopause. Postmenopausal women with early menarche age, long menstrual cycle, age of menopause, and length of menopause should be screened in advance to prevent the occurrence of osteoporosis.

关 键 词：兰州市 月经史 女性 骨质疏松症 

分 类 号：R181[医药卫生—流行病学]