我院外科送检血标本病原菌分布及耐药情况分析  

Analysis on the Distribution and Drug Resistance of Pathogenic Bacteria in Blood Specimen Submitted by Surgery in the Sixth Affiliated Hospital of Guangzhou Medical University

作　　者：彭晓飞[1] 陈凌娟 Peng Xiaofei(Department of Laboratory Medicine,The Sixth Affiliated Hospital of Guangzhou Medical University/Qingyuan People's Hospital,Qingyuan Guangdong 511518)

机构地区：[1]广州医科大学附属第六医院/清远市人民医院检验科,广东清远511518

出　　处：《黑龙江医药》2022年第5期1043-1045,共3页Heilongjiang Medicine journal

基　　金：清远市社会发展领域自筹经费科技计划立项项目(编号:2019124)。

摘　　要：目的:探讨广州医科大学附属第六医院外科送检血标本病原菌分布特点及耐药情况。方法:回顾性分析2018年1月至2020年12月我院外科住院血流感染患者100例的临床资料,共收集血培养标本100份,进行细菌鉴定及药敏试验。分析我院外科送检血标本病原菌分布特点及耐药性。结果:100例患者中血培养共检出病原菌112株,其中革兰阴性菌67株,占59.82%,以大肠埃希菌(24.11%)、肺炎克雷伯菌(17.86%)为主;其次为革兰阳性菌38株,占33.93%,以表皮葡萄球菌(15.18%)为主;大肠埃希菌和肺炎克雷伯菌对头孢唑林(KZ)、哌拉西林(PIP)、头孢呋辛(CXM)等有较强的耐药性,表皮葡萄球菌对青霉素G(PG)、红霉素(ERY)、环丙沙星(CIP)等有较强的耐药性。结论:医院外科送检血标本病原菌以大肠埃希菌、肺炎克雷伯菌、表皮葡萄球菌为主,且耐药性较高,临床需加强监测病原菌,合理应用抗菌药,以达到控制外科感染的目的。Objective:To investigate the distribution characteristics and drug resistance of pathogenic bacteria in blood specimens submitted for examination in the Sixth Hospital of Guangzhou Medical University.Methods:A retrospective analysis of the clinical data of 100 patients with bloodstream infection in our hospital from January 2018 to December 2020.A total of 100 blood culture specimens were collected for bacterial identification and drug susceptibility testing.Analyze the distribution characteristics and drug resistance of pathogenic bacteria in blood samples submitted by our hospital for examination.Results:A total of 112 pathogens were detected in blood culture in 100 patients,of which 67 were gram-negative bacteria,accounting for 59.82%,with Escherichia coli(24.11%)and Klebsiella pneumoniae(17.86%)as the main ones;38 strains of gram-positive bacteria,accounting for 33.93%,mainly Staphylococcus epidermidis(15.18%);Xin(CXM)has strong drug resistance,and Staphylococcus epidermidis has strong drug resistance to penicillin G(PG),erythromycin(ERY),and ciprofloxacin(CIP).Conclusion:The pathogenic bacteria in blood specimens submitted for examination in hospital surgery are mainly Escherichia coli,Klebsiella pneumoniae,and Staphylococcus epidermidis,and their drug resistance is high.It is necessary to strengthen clinical monitoring of pathogens and rational use of antibiotics to control the goal of surgical infections.

关 键 词：外科 血标本 病原菌 耐药性 感染 

分 类 号：R446.11[医药卫生—诊断学]