中药定向透药联合红外线治疗功能性腹泻肾阳亏虚证的临床观察  

Clinical Observation on the Functional Diarrhea with Kidney Yang Deficiency Syndrome by Directional Chinese Herbal Penetration Combined with Infrared

作　　者：顾志坚[1] 耿琦[1] 丛军[1] 蔡淦[1] 李莉[1] GU Zhijian;GENG Qi;CONG Jun;CAI Gan;LI Li(Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200021,China)

机构地区：[1]上海中医药大学附属曙光医院,上海200021

出　　处：《中医药导报》2022年第9期71-74,79,共5页Guiding Journal of Traditional Chinese Medicine and Pharmacy

基　　金：首届全国名中医传承工作室建设项目(MZYGZS-2017003);上海市第七批全国老中医药专家学术经验继承项目。

摘　　要：目的:观察中药定向透药联合红外线治疗功能性腹泻肾阳亏虚证的疗效。方法:将142例功能性腹泻肾阳亏虚证患者采用随机数字表分为治疗组和对照组,每组71例。治疗组患者予中药定向透药联合红外线治疗,每周3次,对照组患者口服马来酸曲美布汀胶囊(0.2 g/次,3次/d)和酪酸梭活菌片(40 mg/次,3次/d),疗程为4周。比较治疗前后两组患者每日大便次数、Bristol粪便性状评分、中医证候积分、中医证候疗效以及治疗3个月后的复发率。结果:治疗2周、4周后,两组患者大便次数和Bristol粪便性状评分均低于治疗前(P<0.05);治疗组患者Bristol粪便性状评分低于对照组(P<0.05)。治疗2周、4周后,两组患者中医证候积分均低于治疗前(P<0.05),且治疗组患者中医证候积分均低于对照组(P<0.05)。治疗4周后,治疗组中医证候疗效总有效率为94.37%(67/71),对照组中医证候疗效总有效率为81.69%(58/71),治疗组优于对照组(P<0.05)。治疗3个月后,治疗组复发率[31.34%(21/67)]低于对照组[58.62%(34/58)],差异有统计学意义(P<0.05)。结论:中药定向透药联合红外线治疗功能性腹泻肾阳亏虚证有较好疗效。Objective:To observe the curative effect of directional Chinese herbal penetration combined with infrared in the treatment of functional diarrhea with kidney Yang deficiency syndrome.Methods:Totally 142 cases of patients with functional diarrhea of kidney Yang deficiency syndrome were divided into treatment and control groups according to the random number table,71 cases in each group.Patients were treated with directional Chinese herbal penetration combined with infrared in treatment group,3 times a week.Patients were given trimebutine maleate(0.2 g/time,three times a day)and Clostridium butyricum tablets(40 mg/time,three times a day)in control group.The patients were treated for four weeks in two groups.The changes of daily stool frequency,Bristol Stool Form Scale,TCM syndrome score,curative effect of TCM syndrome and the recurrence rate after 3 months were compared between the two groups.Results:After 2 and 4 weeks of treatment,the stool frequency and Bristol Stool Form Scale of the two groups were lower than those before treatment(P<0.05),and the treatment group showed lower Bristol Stool Form Scale than control group(P<0.05).After 2 and 4 weeks of treatment,the TCM syndrome scores of the two groups were lower than those before treatment(P<0.05),and the treatment group showed lower TCM syndrome score than control group(P<0.05).After 4 weeks of treatment,the total effective rate of TCM syndrome was 94.37%(67/71)in treatment group and 81.69%(58/71)in control group.The treatment group showed better effect than control group(P<0.05).After 3 months of treatment,the recurrence rate was 31.34% (21/67) in treatment group and 58.62% (34/58) in control group. The treatment group showed lower recurrence rate than control group (P<0.05). Conclusions: Directional Chinese herbal penetration combined with infrared is an effective method for functional diarrhea with kidney Yang deficiency syndrome.

关 键 词：功能性腹泻 肾阳亏虚证 中药定向透药 红外线 马来酸曲美布汀胶囊 酪酸梭活菌片 

分 类 号：R256.34[医药卫生—中医内科学]