中药外敷促进腹部术后胃肠功能恢复的Meta分析  

Meta-analysis of External Therapy of Traditional Chinese Medicine to Promote Recovery of Gastrointestinal Function after Abdominal Surgery

作　　者：黄艳雄 甘华婵 王婕[3] 曹立幸 HUANG Yan-xiong;GAN Hua-chan;WANG Jie(The Second Clinical College of Guangzhou University of Chinese Medicine,Guangzhou(510006),China)

机构地区：[1]广州中医药大学第二临床医学院,广州510006 [2]广州中医药大学第二附属医院围手术期团队,广州510120 [3]北京中医药大学深圳医院妇科,广东深圳518172

出　　处：《中国中西医结合外科杂志》2022年第5期655-664,共10页Chinese Journal of Surgery of Integrated Traditional and Western Medicine

基　　金：国家区域中医(专科)诊疗中心建设专项资金资助(国中医药医政函(2018)205号广东省中医院外科);广东省中医院临床研究专项(YN10101902);广东省中医院临床研究专项(YN10101911);广东省中医院中医药科学技术研究专项(YN2021MS01);广州中医药大学“双一流”与高水平大学学科协同创新团队项目(2021xk48);广州中医药历史文化研究基地项目(Y202103);广东省中医药局科研项目(20211119);全国中医药高等教育“十四五”规划2021年度课题(ZC-20-01)。

摘　　要：目的:通过Meta分析的方法探讨中药外敷对腹部术后胃肠功能恢复的作用。方法:计算机检索中国知网期刊全文数据库(CNKI)、维普期刊数据库(VIP)、万方数据知识服务平台(Wanfang)、中国生物医学文献数据库(CBM)、美国医学在线(PubMed)数据库关于中药外敷促进腹部术后胃肠功能恢复的随机对照试验(RCT)研究文献,检索时限均为建库至2021年11月1日,筛选文献、提取资料并对相关的文献进行质量评价后,采用RevMan 5.3软件进行Meta分析。结果:共纳入16篇文献,包括2628例患者,Meta分析结果:与对照组相比,中药外敷组在缩短术后首次排气时间方面,SMD=-10.06,95%CI[-11.56,-8.57],P<0.001;在缩短术后首次排便时间方面,SMD=-11.92,95%CI[-15.54,-8.29],P<0.001;在缩短术后肠鸣音恢复时间方面,SMD=-7.50,95%CI[-10.01,-4.99],P<0.001;在临床疗效方面,试验组治疗有效率明显高于对照组,RR=1.34,95%CI[1.21,1.47],P<0.001。结论:当前证据表明中药外敷对腹部术后胃肠功能恢复具有积极作用,但受纳入研究数量和质量的限制,故其作用还需更多高质量研究进一步验证。Objective To explore the effect of external therapy of Traditional Chinese Medicine on recovery of gastrointestinal function after abdominal surgery by Meta-analysis method.Methods Computer retrieval of Pub Med,CNKI,VIP,CBM,Wanfang Data were performed.The clinical randomized controlled trial(RCT)of external treatment of TCM on recovery of gastrointestinal function after abdominal surgery was searched,and the retrieval time was from the time of building the database November 1st,2021.The literature was screened,the data were extracted,and the quality was evaluated.The Revman5.3 software was used for Meta analysis.Results A total of 16 RCTs involving 2628 patients were included.The results of the Meta-analysis indicated that:compared between both groups,external therapy of Traditional Chinese Medicine shortened the postoperative initial exhaust time,SMD=-10.06,95%CI[-11.56,-8.57],P<0.001;reduced the postoperative first defecation time,SMD=-11.92,95%CI[-15.54,-8.29],P<0.001;speeded up the initial recovery of bowel sounds,SMD=-7.50,95%CI[-10.01,-4.99],P<0.001;enhanced the effective rate,RR=1.34,95%CI[1.21,1.47],P<0.001.Conclusion Current evidence shows that the external therapy of Traditional Chinese Medicine has a positive clinical effect on recovery of gastrointestinal function after abdominal surgery.But limited quality and quantity of the included studies,more high-quality studies are required to verify the above conclusion.

关 键 词：中药外敷 腹部术后 胃肠功能 META分析 

分 类 号：R244.9[医药卫生—针灸推拿学]