BiPAP呼吸机治疗重度哮喘的疗效观察  

Observation on the efficacy of BiPAP ventilator in the treatment of severe asthma

作　　者：濮娜[1] 吴莹[1] 王振宇[1] PU Na;WU Ying;WANG Zhen-yu(Department of Critical Care Medicine,Xinhua Hospital Affiliated to Dalian University,Dalian 116000,China)

机构地区：[1]大连大学附属新华医院重症医学科,116000

出　　处：《中国实用医药》2022年第20期56-58,共3页China Practical Medicine

摘　　要：目的分析双水平气道正压通气(BiPAP)呼吸机治疗重度哮喘的疗效。方法80例重度哮喘患者,随机分为对照组和观察组,每组40例。对照组患者采用常规呼吸机辅助治疗,观察组患者采用BiPAP呼吸机治疗。比较两组治疗第1、3、5天的肺功能指标[第1秒用力呼气容积(FEV1)、用力肺活量(FVC)以及FEV1/FVC]及机械通气时间、重症加强护理病房(ICU)住院时间以及总住院时间。结果治疗第3天,观察组患者FEV1、FVC以及FEV1/FVC分别为(2.23±0.43)L、(2.67±0.23)L、(65.34±0.17)%,对照组患者分别为(1.90±0.45)L、(2.56±0.34)L、(60.12±0.13)%;治疗第5天,观察组患者FEV1、FVC以及FEV1/FVC分别为(2.98±0.67)L、(3.89±0.65)L、(71.28±5.43)%,对照组患者分别为(2.04±0.79)L、(2.90±0.53)L、(65.31±5.34)%;治疗第3、5天,观察组患者FEV1、FVC以及FEV1/FVC均高于对照组,差异具有统计学意义(P<0.05)。观察组患者的机械通气时间、ICU住院时间以及总住院时间分别为(7.31±1.13)、(10.24±1.58)、(14.22±1.53)d,均短于对照组的(10.89±1.34)、(13.26±1.34)、(17.45±1.12)d,差异具有统计学意义(P<0.05)。结论BiPAP呼吸机用于重度哮喘治疗中疗效显著,患者的肺功能得到明显改善,且能够有效促进患者的后期康复,具有较高的临床应用价值。Objective To analyze the efficacy of bi-level positive airway pressure(BiPAP)ventilator in the treatment of severe asthma.Methods A total of 80 patients with severe asthma were randomly divided into control group and observation group,with 40 cases in each group.Patients in the control group were treated with conventional ventilator assisted therapy,and patients in the observation group were treated with BiPAP ventilator.The pulmonary function indexes[forced expiratory volume in the 1st second(FEV1),forced vital capacity(FVC)and FEV1/FVC]on the 1st,3rd,and 5th day of treatment,mechanical ventilation time,duration of intensive care unit(ICU)stay,and total hospital stay were compared between the two groups.Results On the 3rd day of treatment,the FEV1,FVC and FEV1/FVC of the observation group were(2.23±0.43)L,(2.67±0.23)L and(65.34±0.17)%,and those of the control group were(1.90±0.45)L,(2.56±0.34)L and(60.12±0.13)%;on the 5th day of treatment,the FEV1,FVC and FEV1/FVC of the observation group were(2.98±0.67)L,(3.89±0.65)L and(71.28±5.43)%,and those of the control group were(2.04±0.79)L,(2.90±0.53)L and(65.31±5.34)%;on the 3rd and 5th day of treatment,the FEV1,FVC and FEV1/FVC of the observation group were higher than those of the control group,and the differences were statistically significant(P<0.05).The mechanical ventilation time,duration of ICU stay and total hospital stay of the observation group were(7.31±1.13),(10.24±1.58)and(14.22±1.53)d,which were shorter than(10.89±1.34),(13.26±1.34)and(17.45±1.12)d of the control group,and the differences were statistically significant(P<0.05).Conclusion Bi PAP ventilator has a significant effect in the treatment of severe asthma,and can significantly improve the lung function of patients,and effectively promote the later recovery of patients,which has high clinical application value.

关 键 词：双水平气道正压通气呼吸机 重度哮喘 疗效 

分 类 号：R562.25[医药卫生—呼吸系统]