丙泊酚复合芬太尼在无痛支气管镜检查中的应用效果  

Application Effects of Propofol Combined Fentanyl in Painless Bronchoscopy

作　　者：白贯银 刘俊沛 陈君 BAI Guanyin;LIU Junpei;CHEN Jun(Department of Respiratory and Critical Care Medicine,Yuzhou People’s Hospital,Xuchang 461670,China)

机构地区：[1]禹州市人民医院呼吸与危重症医学科,河南许昌461670

出　　处：《河南医学研究》2022年第19期3579-3582,共4页Henan Medical Research

摘　　要：目的 探讨丙泊酚复合芬太尼在无痛支气管镜检查中的应用效果。方法 选取2020年5月至2021年12月在禹州市人民医院接受支气管镜检查的90例患者为研究对象。根据麻醉方式分为对照组和观察组,观察组(45例)检查前接受丙泊酚复合芬太尼进行全身麻醉,对照组(45例)检查前接受2 g·L^(-1)利多卡因咽部、气管局部麻醉。观察两组患者不同时间点的收缩压(SBP)、舒张压(DBP)、心率(HR)、血氧饱和度(SpO_(2))变化,比较两组患者生命体征情况、检查中不良反应情况及对检查的主观评价情况。结果 对照组检查中SBP、DBP、HR、SpO_(2)均高于麻醉前(P<0.05),检查结束后HR高于麻醉前(P<0.05);检查中观察组SBP、DBP、HR、SpO_(2)均高于对照组(P<0.05),检查结束后观察组HR高于对照组(P<0.05);观察组检查中发生呛咳、体动及呼吸困难例数低于对照组(P<0.05);观察组发生术后不良记忆与咽部不适例数低于对照组,愿意接受复查的人数高于对照组(P<0.05)。结论 丙泊酚复合芬太尼在老年无痛支气管镜检查中起效快,麻醉作用强,安全性高,不良反应及不良记忆少,可减轻患者痛苦,使患者易于接受,值得临床广泛推广。Objective To investigate the application effects of propofol combined with fentanyl in painless bronchoscopy.Methods Ninety patients who underwent bronchoscopy in Yuzhou People’s Hospital from May 2020 to December 2021 were selected as the study subjects.According to anesthesia methods,they were divided into observation group and control group.The observation group(45 cases) accepted general anesthesia with propofol and fentanyl before examination,the control group(45 cases) accepted local anesthesia with 2 g·L^(-1) lidocaine in the pharynx and trachea before examination.The changes of systolic blood pressure(SBP),diastolic blood pressure(DBP),heart rate(HR) and oxygen saturation(SpO_(2)) at different time points were observed.The vital sign conditions,adverse reactions during examination and subjective evaluation of the examination were compared between the two groups.Results In control group,SBP,DBP,HR and SpO_(2) on examination were higher than those before anesthesia(P<0.05),and HR after examination was higher than before anesthesia(P<0.05).SBP,DBP,HR and SpO_(2) on examination in observation group were higher than those in control group(P<0.05),and HR after examination was higher than that in control group(P<0.05).The number of cases of choking,body movement and dyspnea in observation group was lower than that in control group(P<0.05).The number of cases of postoperative bad memory and pharyngeal discomfort in observation group was lower than that in control group,and the number of people willing to accept reexamination was higher than that in control group(P<0.05).Conclusion Propofol combined with fentanyl in painless bronchoscopy has the characteristics of rapid onset,strong anesthetic effect,high safety,adverse reactions and less adverse memory,which can reduce the pain of patients and is easily accepted by patients.It is worthy of being widely popularized in the clinical application.

关 键 词：丙泊酚 芬太尼 支气管镜检查 无痛 

分 类 号：R614.3[医药卫生—麻醉学]