经典名方瓜蒌薤白半夏汤药物炮制品种及处方剂量的文献考证  

Textual Research on the Variety of Processing Medicinals and Prescription Dosage of the Classic Formula:Gualou Xiebai Banxia Decoction

作　　者：王元彪 沈劼 WANG Yuan-biao;SHEN Jie(Institute of Literature in Chinese Medicine,Nanjing University of Chinese Medicine,Nanjing 210023,China)

机构地区：[1]南京中医药大学中医药文献研究所,江苏南京210023

出　　处：《南京中医药大学学报》2022年第9期831-838,共8页Journal of Nanjing University of Traditional Chinese Medicine

基　　金：江苏高校优秀学科建设工程资助项目(PAPD);国家中医药管理局基金项目(GZY-KJS-2021-027);中医药古籍文献和特色技术传承专项(GZY-KJS-2020-065);江苏省社会科学基金(20LSD002);江苏高校哲学社会科学研究基金(2017SJB0299)。

摘　　要：通过收集中医古籍文献数据,结合中医临床用药经验和现代中药药理学研究成果,对瓜蒌薤白半夏汤的药物炮制品种及处方剂量进行系统梳理与考证分析,为经典名方的研发与临床应用提供文献依据。经考证,瓜蒌薤白半夏汤中的“白酒”为低度米酒(酒精浓度10%~20%),其余药物炮制品种应选用生瓜蒌、生薤白、姜半夏。研究发现,半夏剂量应选择吴迁本“半夏半升”为宜。瓜蒌薤白半夏汤标准剂量为瓜蒌55.422 g,薤白46.875 g,姜半夏61.990 g,白酒2000 mL,现代中医临床参考用量为瓜蒌15 g,薤白12 g,姜半夏16 g,白酒500 mL。By collecting data from ancient traditional Chinese medical(TCM)texts,combining the clinical experience of TCM practitioners and modern pharmacological research results of Chinese medicine,we systematically analyzed the variety of processing medicinals and prescription dosage of Gualou Xiebai Banxia decoction,to provide a textual reference for the development and clinical application of the classic formula.It was proved that the"white wine"in Gualou Xiebai Banxia decoction was mild rice wine(alcohol content:10%-20%),and the rest of the variety of processing medicinals should be raw Gualou,raw Xiebai and ginger processed Banxia.In addition,it was found that the dosage of Banxia should be half-liter(reference to the Essentials from the Golden Cabinet of Wu Qian's version).The modern TCM clinical reference dosage of the classic formula is listed as follows:Gualou 15 g,Xiebai 12 g,Banxia 16 g,and white wine 500 mL.

关 键 词：瓜蒌薤白半夏汤 经典名方 金匮要略 文献考证 

分 类 号：R289.1[医药卫生—方剂学]