Mental Calculation Drives Reliable and Weak Distant Connectivity While Music Listening Induces Dense Local Connectivity  

作　　者：Gaoxing Zheng Yuzhu Li Xiaoying Qi Wei Zhang Yuguo Yu 

机构地区：[1]State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science,Human Phenome Institute and Research Institute of Intelligent and Complex Systems,Institute of Science and Technology for Brain-Inspired Intelligence,Shanghai 200433,China [2]Department of Neurology,Zhongshan Hospital and Shanghai Medical College,Fudan University,Shanghai 200032,China

出　　处：《Phenomics》2021年第6期285-298,共14页表型组学（英文）

基　　金：YY thanks for the support from the National Natural Science Foundation of China(81761128011);the Shanghai Municipal Science and Technology Major Project(2018SHZDZX01);ZJ Lab,the program for the Professor of Special Appointment(Eastern Scholar)at Shanghai Institutions of Higher Learning.

摘　　要：Mathematical calculation usually requires sustained attention to manipulate numbers in the mind,while listening to light music has a relaxing effect on the brain.The differences in the corresponding brain functional network topologies underlying these behaviors remain rarely known.Here,we systematically examined the brain dynamics of four behaviors(resting with eyes closed and eyes open,tasks of music listening and mental calculation)using 64-channel electroencephalogram(EEG)recordings and graph theory analysis.We developed static and dynamic minimum spanning tree(MST)analysis method and demonstrated that the brain network topology under mental calculation is a more line-like structure with less tree hierarchy and leaf fraction;however,the hub regions,which are mainly located in the frontal,temporal and parietal regions,grow more stable over time.In contrast,music-listening drives the brain to exhibit a highly rich network of star structure,and the hub regions are mainly located in the posterior regions.We then adopted the dynamic dissimilarity of different MSTs over time based on the graph Laplacian and revealed low dissimilarity during mental calculation.These results suggest that the human brain functional connectivity of individuals has unique dynamic diversity and flexibility under various behaviors.

关 键 词：Dynamic minimum spanning tree Spatiotemporal variability DISSIMILARITY Graph Laplacian Mental calculation Music listening 

分 类 号：H31[语言文字—英语]