晚期妊娠羊水过少羊膜腔灌注联合缩宫素引产的临床效果分析  

Analysis of Clinical Effect of Amniotic Cavity Perfusion Combined with Oxytocin Induction of Labor in Late Pregnancy with Oligohydramnios

作　　者：杨爱菊 YANG Aiju(Fuzhou Fuxing Maternity Hospital,Fuzhou 350001,China)

机构地区：[1]福州福兴妇产医院,福建福州350001

出　　处：《中外医学研究》2022年第26期138-142,共5页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探讨羊膜腔灌注联合缩宫素引产对羊水过少足月孕妇的临床疗效及对妊娠结局的影响。方法:选取2021年1月-2022年3月福州福兴妇产医院收治的100例晚期妊娠羊水过少孕妇为研究对象,所有孕妇在“知情同意”原则下分为观察组和对照组,每组50例。观察组实行羊膜腔灌注联合缩宫素引产,对照组实行缩宫素引产。评估两组羊水指数、胎儿脐动脉及大脑中动脉参数、分娩方式、总产程、新生儿出生相关指标并进行组间比较。结果:观察组较对照组自然分娩率更高,剖宫产率更低(P<0.05)。观察组阴道分娩总产程较对照组短(P<0.05)。治疗后,观察组孕妇AFI水平明显高于对照组(P<0.05)。治疗后,观察组胎儿UA-S/D、UA-RI水平均低于对照组,UA-PI水平高于对照组(P<0.05),MCA-PSV虽高于对照组,但差异无统计学意义(P>0.05)。观察组羊水浑浊、新生儿窒息、转新生儿ICU发生率及新生儿脐动脉血乳酸水平较对照组均更低,观察组新生儿脐动脉血pH值、1 min Apgar评分高于对照组(P<0.05)。两组不良事件发生率比较,差异无统计学意义(P>0.05)。结论:晚期妊娠羊水过少实施羊膜腔灌注联合缩宫素引产,可以提高羊水量,降低剖宫产率,促进自然分娩,改善母婴结局、提高新生儿出生相关指标。Objective:To investigate the clinical effect of amniotic cavity perfusion combined with Oxytocin induction on term pregnant women with oligohydramnios and its influence on pregnancy outcome.Method:A total of 100 pregnant women with oligohydramnios in late pregnancy who were admitted to Fuzhou Fuxing Maternity Hospital from January 2021 to March 2022 were selected as the research objects,all pregnant women were divided into observation group and control group under the principle of “informed consent”,with 50 cases in each group.The observation group was induced by amniotic cavity perfusion combined with Oxytocin,while the control group was induced by Oxytocin.Amniotic fluid index,fetal umbilical artery and middle cerebral artery parameters,delivery mode,total labor time,neonatal birth related indicators were evaluated and compared between the two groups.Result:The natural delivery rate of the observation group was higher and the cesarean section rate was lower than that of the control group (P<0.05).The total course of vaginal delivery in the observation group was shorter than that in the control group (P<0.05).After treatment,the AFI level of pregnant women in the observation group was significantly higher than that in the control group (P<0.05).After treatment,the levels of UA-S/D and UA-RI of the fetuses in the observation group were lower than those in the control group,and the level of UA-PI was higher than that in the control group (P<0.05),although the level of MCA-PSV was higher than that in the control group,the difference was not statistically significant (P>0.05).The incidence of amniotic fluid turbidity,neonatal asphyxia,neonatal ICU transfer and neonatal umbilical artery blood lactate level in the observation group were lower than those in the control group,the pH value of umbilical artery blood and 1 min Apgar score in the observation group were higher than those in the control group (P<0.05).There was no significant difference in the incidence of adverse events between the two groups (P>0.05).Co

关 键 词：晚期妊娠孕妇 羊水过少 羊膜腔灌注 缩宫素 引产 

分 类 号：R719.3[医药卫生—妇产科学]