Systematic Review and Meta-Analysis of Acupuncture for Pain Caused by Liver Cancer  

作　　者：Xiao-Wen Zhang Yun-Jia Gu Huan-Gan Wu Kun-Shan Li Rui Zhong Qin Qi Pin Wu Jun Ji Hui-Rong Liu Yan Huang Chang-Gue Son Lu-Yi Wu 

机构地区：[1]Shanghai Research Institute of Acupuncture and Meridian,Yueyang Hospital of Integrated Traditional Chinese and Western Medicine,Shanghai University of Traditional Chinese Medicine,Shanghai,China [2]Shanghai Qigong Research Institute,Shanghai University of Traditional Chinese Medicine,Shanghai,China [3]Key Laboratory of Acupuncture and Immunological Effects,Shanghai University of Traditional Chinese Medicine,Shanghai,China [4]Shanghai Research Institute of Acupuncture and Meridian,Yueyang Hospital of Integrated Traditional Chinese and Western Medicine,Key Laboratory of Acupuncture and Immunological Effects,Shanghai University of Traditional Chinese Medicine,Shanghai,China [5]Liver and Immunology Research Center,Daejeon Oriental Hospital of Daejeon University,Korea [6]Shanghai Qigong Research Institute,Key Laboratory of Acupuncture and Immunological Effects,Shanghai University of Traditional Chinese Medicine,Shanghai,China

出　　处：《World Journal of Traditional Chinese Medicine》2022年第3期402-412,共11页世界中医药杂志（英文）

基　　金：supported by Key Project of Chinese National Programs for Fundamental Research and Development(973 Program)(No.2009CB522900,No.2015CB554501);the Project of Three-Year Action Plan for development of traditional Chinese medicine in Shanghai(No.ZY(2018-2020)-CCCX-2004-01);Shanghai Clinical Research Center for Acupuncture and Moxibustion(No.20MC1920500)。

摘　　要：Objective:The objective of this study is to systematically review and analyze the efficacy of acupuncture for pain caused by primary liver cancer(PLC).Materials and Methods:We searched databases,including PubMed,Medline,Embase,Cochrane Library,Web of Science,China National Knowledge Infrastructure,Chinese Science and Technology Periodicals Database(VIP),Wanfang,and SinoMed/Chinese Biomedical Database(CBM),and retrieved randomized controlled trials(RCTs)that used acupuncture as the primary intervention to treat pain caused by PLC.Two investigators then screened the articles,extracted and pooled data,and evaluated the risk of bias of the included articles according to the Cochrane Handbook.RevMan5.3 was used for the meta-analysis of eligible RCTs.Results:A total of 145 articles were retrieved;after screening,8 RCTs involving 496 patients were eventually included in this meta-analysis.The results showed that acupuncture effectively improved cancer pain and was superior to Western medicine.Moreover,acupuncture was fast-acting for pain relief,prolonged the relief,and prevented relapse.Its adverse reaction rate was also significantly lower than that of Western medicine.No significant difference was observed in Visual Analog Scale score between acupuncture and Western medicine.Conclusion:Acupuncture relieves pain caused by liver cancer and can be used as an adjunct and alternative therapy for drug treatment.The existing research evidence is not yet objective or comprehensive,and more rigorous clinical trials are needed to validate the results.

关 键 词：ACUPUNCTURE liver cancer META-ANALYSIS PAIN systematic review 

分 类 号：R246.5[医药卫生—针灸推拿学]