不同亚型慢性失眠患者认知功能的差异性分析  

Differential analysis of cognitive function in patients with different subtypes of chronic insomnia

作　　者：金亚萍 史丽娜 范学文 JIN Yaping;SHI Lina;FAN Xuewen(Ningxia Medical University,Yinchuan 750004,China)

机构地区：[1]宁夏医科大学,宁夏银川750004 [2]宁夏医科大学总医院心脑血管病医院神经内科,宁夏银川750004

出　　处：《中风与神经疾病杂志》2022年第9期803-807,共5页Journal of Apoplexy and Nervous Diseases

摘　　要：目的探索慢性失眠各亚型间认知功能障碍的发生率及所损害的认知域有何不同。方法收集2018年1月至2018年12月就诊于我院神经内科门诊诊断为慢性失眠的病例,按纳入排除标准共收集病例65例,应用多导睡眠监测(Polysonmography,PSG)对患者进行失眠客观分型,其中入睡困难型14例、早醒型12例、维持困难型16例、混合型23例,在完成PSG检查的次日上午应用蒙特利尔认知量表(Montreal Cognitive Assessment,MoCA)对患者行认知功能评估,经统计学方法寻找不同亚型慢性失眠患者认知功能的差异性。结果(1)慢性失眠患者不同亚型间认知功能障碍的发生率不同(χ^(2)=8.004,P<0.05),混合型更易发生认知功能障碍;(2)不同亚型慢性失眠患者的延迟回忆得分有差异(H=13.239,P<0.05),混合型的延迟回忆得分低于其他型(P<0.05)。结论不同亚型慢性失眠患者认知功能障碍的发生率不同,混合型更易发生认知障碍;各亚型间延迟回忆能力不同,混合型更差。Objective To explore the differences in cognitive function between different subtypes of chronic insomnia,including the diferences of incidence of cognitive dysfunction and the cognitive domain of each subtype.Methods To collect patients diagnosed as chronic insomnia in the neurology department of Cardiovascular and Cerebrovascular Hospital of Ningxia Medical University from January 2018 to December 2018(65 cases in total).Polysomnography(PSG)was used to classify patients with insomnia objectively.14 cases were sleep difficultly,12 cases were awakened early,16 cases were difficult to maintain,and 23 cases were mixed.On the morning of the completion of PSG,to evaluate the cognitive function of patients with the Montreal Cognitive Assessment(MoCA).Results(1)The incidence of cognitive impairment in different subtypes of chronic insomnia was different(χ^(2)=8.004,P<0.05),and the mixed group was more prone to cognitive dysfunction.(2)The delayed recall scores of patients with different subtypes of insomnia were different(H=13.239,P<0.05),and the scores of the mixed group were lower than other groups(P<0.05).Conclusion The incidence of cognitive dysfunction among different subtypes of chronic insomnia was different,the mixed type was more prone to cognitive impairment.The delayed recall ability varied among different types,the mixed type was worse.

关 键 词：慢性失眠 认知功能 多导睡眠监测 蒙特利尔认知量表 

分 类 号：R338.63[医药卫生—人体生理学]