多层螺旋CT轴位、MPR技术在多重耐药结核中的应用  

Application of Multi-slice Spiral CT Axial Position and MPR Technique in Multidrug-resistant Tuberculosis

作　　者：李蔚宇[1] 袁光峰 唐城 LI Weiyu;YUAN Guangfeng;TANG Cheng(Guangzhou Chest Hospital,Guangzhou 510095,China;不详)

机构地区：[1]广州市胸科医院,广东广州510095

出　　处：《中外医学研究》2022年第24期63-68,共6页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探讨多层螺旋CT轴位、多平面重建(MPR)技术在多重耐药结核中的应用。方法:选取2019年1月-2020年12月广州市胸科医院100例疑似多重耐药结核患者作为研究对象。所有患者均行多层螺旋CT轴位及多层螺旋CT MPR技术检查及联合检查。以手术或穿刺病理及药敏试验检查结果作为“金标准”,分析多层螺旋CT轴位、MPR技术、联合检查多重耐药结核结果,比较不同检查方法诊断效能。结果:100例疑似多重耐药结核患者经“金标准”检查最终确诊67例,确诊率为67.00%;多层螺旋CT轴位检查最终诊断出56例,与金标准诊断符合率为77.00%(77/100)。多层螺旋CT轴位诊断敏感度为74.63%(50/67),特异度为81.82%(27/33),阳性预测值为89.29%(50/56),阴性预测值61.36%(27/44)。多层螺旋CT MPR技术检查最终诊断出61例,与金标准诊断符合率为78.00%(78/100)。多层螺旋CT MPR技术诊断敏感度为79.10%(53/67),特异度为75.76%(25/33),阳性预测值为86.89%(53/61),阴性预测值64.10%(25/39)。多层螺旋CT轴位联合MPR技术检查最终诊断出65例,与金标准诊断符合率为92.00%(92/100)。联合检查诊断敏感度为92.54%(62/67),特异度为90.91%(30/33),阳性预测值为95.38%(62/65),阴性预测值85.71%(30/35)。联合检查诊断多重耐药结核敏感度、阴性预测值高于多层螺旋CT轴位、多层螺旋CT MPR检查(P<0.05)。结论:多层螺旋CT轴位与MPR技术可用于多重耐药结核诊断中,且二者联合能提高诊治敏感度与阴性预测值,为临床诊疗提供影像学依据。Objective:To investigate the application of multi-slice spiral CT axial position and multi-plane reconstruction (MPR) technique in multidrug-resistant tuberculosis.Method:From January 2019 to December 2020,100 patients suspected multidrug-resistant tuberculosis in Guangzhou Chest Hospital were selected as the research objects.All patients underwent multi-slice spiral CT axial position and multi-slice spiral CT MPR technique and joint examination.Taking the results of surgery or puncture pathology and drug sensitivity test as the “gold standard”,the results of multi-slice spiral CT axial position,MPR technology and joint examination for multidrug-resistant tuberculosis were analyzed,and the diagnostic efficacy of different examination methods was compared.Result:A total of 67 cases of 100 suspected multidrug-resistant tuberculosis patients were finally diagnosed by “gold standard” examination,and the diagnosis rate was 67.00%;56 cases were finally diagnosed by multi-slice spiral CT axial position examination,and the coincidence rate with the gold standard diagnosis was 77.00% (77/100).The sensitivity of multi-slice spiral CT axial position diagnostic was 74.63% (50/67),the specificity was 81.82% (27/33),the positive predictive value was 89.29% (50/56),and the negative predictive value was 61.36% (27/44).61 cases were finally diagnosed by multi-slice spiral CT MPR,and the coincidence rate with the gold standard diagnosis was 78.00% (78/100).The diagnostic sensitivity of multi-slice spiral CT MPR technique was 79.10% (53/67),the specificity was 75.76% (25/33),the positive predictive value was 86.89% (53/61),and the negative predictive value was 64.10% (25/39).65 cases were finally diagnosed by multi-slice spiral CT axial position combined with MPR technique,and the coincidence rate with the gold standard diagnosis was 92.00% (92/100).The combined diagnostic sensitivity was 92.54% (62/67),the specificity was 90.91% (30/33),the positive predictive value was 95.38% (62/65),and the negative predictive value was

关 键 词：多层螺旋CT 多平面重建 多重耐药结核 诊断效能 

分 类 号：R52[医药卫生—内科学] R816[医药卫生—临床医学]