New discovery of high-affinity SARS-CoV-2 spike S2 protein binding peptide selected by PhIP-Seq  

作　　者：Mengyuan Chen Shuizhen He Hualong Xiong Dongxu Zhang Shaojuan Wang Wangheng Hou Xiaomei Zhu Jin Wang Yang Huang Congming Hong Yubin Wu Ruoyao Qi Tianying Zhang Quan Yuan Tingdong Li Yixin Chen Shiyin Zhang Shengxiang Ge Jun Zhang Ningshao Xia 

机构地区：[1]State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics,National Institute of Diagnostics and Vaccine Development in Infectious Diseases,School of Public Health,Xiamen University,South Xiang'an Road,Xiamen,361102,China [2]Xiamen Haicang Hospital,Haiyu Road,Xiamen,361026,China [3]School of Life Sciences,Xiamen University,South Xiang'an Road,Xiamen,361102,China

出　　处：《Virologica Sinica》2022年第5期758-761,共4页中国病毒学（英文版）

基　　金：supported by the National Key R&D Program of China(grant number 2020YFC0842600);the National Natural Science Foundation of China (grant numbers 82041038 and 31730029)

摘　　要：Dear Editor,Theworld had suffered pandemics of COVID-19 caused by SARS-CoV-2.At the time ofwriting,COVID-19 is still widely spreading inmany countries and regions,and by June 14,2022,totally 532,887,351 cases,including 6,307,021 deaths,were reported globally(WHO,https://covid19.who.int/table).Powerful measures,such as prophylactic and therapeutic interventions against the virus,are in urgent need for COVID-19 control and prevention.The spike protein,which is expressed on the virus surface,is the key determinant of viral-host interaction(Ng et al.,2021)and mediates the virus entry.

关 键 词：PHIP totally 

分 类 号：R373[医药卫生—病原生物学]