Whole-genome resequencing of the wheat A subgenome progenitor Triticum urartu provides insights into its demographic history and geographic adaptation  

作　　者：Xin Wang Yafei Hu Weiming He Kang Yu Chi Zhang Yiwen Li Wenlong Yang Jiazhu Sun Xin Li Fengya Zheng Shengjun Zhou Lingrang Kong Hongqing Ling Shancen Zhao Dongcheng Liu Aimin Zhang 

机构地区：[1]State Key Laboratory of Plant Cell and Chromosome Engineering,National Center for Plant Gene Research,Institute of Genetics and Developmental Biology/Innovation Academy of Seed Design,Chinese Academy of Sciences,Beijing 100101,China [2]State Key Laboratory of North China Crop Improvement and Regulation,College of Agronomy,Hebei Agricultural University,Baoding 071001,China [3]Institute of Vegetables,Zhejiang Academy of Agricultural Sciences,Hangzhou 310021,China [4]BGI Genomics,BGI-Shenzhen,Shenzhen 518083,China [5]State Key Laboratory of Crop Biology,Shandong Key Laboratory of Crop Biology,College of Agronomy,Shandong Agricultural University,Tai’an 271018,China [6]BGI Institute of Applied Agriculture,BGI-Agro,Shenzhen 518120,China

出　　处：《Plant Communications》2022年第5期153-170,共18页植物通讯（英文）

基　　金：This research was financially supported by the National Natural Science Foundation of China(31871617);the Ministry of Science and Technology of the People’s Republic of China(2016YFD0102002 and 2011AA100104).

摘　　要：Triticum urartu is the progenitor of the A subgenome in tetraploid and hexaploid wheat.Uncovering the landscape of genetic variations in T.urartu will help us understand the evolutionary and polyploid characteristics of wheat.Here,we investigated the population genomics of T.urartu by genome-wide sequencing of 59 representative accessions collected around the world.A total of 42.2 million highquality single-nucleotide polymorphisms and 3 million insertions and deletions were obtained by mapping reads to the reference genome.The ancient T.urartu population experienced a significant reduction in effective population size(Ne)from3000000 to140000 and subsequently split into eastern Mediterranean coastal and Mesopotamian-Transcaucasian populations during the Younger Dryas period.A map of allelic drift paths displayed splits and mixtures between different geographic groups,and a strong genetic drift towards hexaploid wheat was also observed,indicating that the direct donor of the A subgenome originated from northwestern Syria.Genetic changes were revealed between the eastern Mediterranean coastal and Mesopotamian-Transcaucasian populations in genes orthologous to those regulating plant development and stress responses.A genome-wide association study identified two single-nucleotide polymorphisms in the exonic regions of the SEMI-DWARF 37 ortholog that corresponded to the different T.urartu ecotype groups.Our study provides novel insights into the origin and genetic legacy of the A subgenome in polyploid wheat and contributes a gene repertoire for genomicsenabled improvements in wheat breeding.

关 键 词：Triticum urartu whole-genome resequencing demographic history geographic adaptation selective sweep GWAS 

分 类 号：S512.1[农业科学—作物学]