Fibrous hamartoma of infancy with bone destruction of the tibia:A case report  

作　　者：Yong-Jie Qiao Wen-Bin Yang Yan-Feng Chang Hao-Qiang Zhang Xin-Yuan Yu Sheng-Hu Zhou Yan-Yan Yang Lv-Dan Zhang 

机构地区：[1]Department of Joint Surgery,The 940th Hospital of Joint Logistic Support Force of the Chinese People's Liberation Army,Lanzhou 730050,Gansu Province,China [2]Department of Orthopedics,The 940th Hospital of Joint Logistic Support Force of Chinese People’s Liberation Army,Lanzhou 730050,Gansu Province,China [3]Department of Cardiology,Yongjing County People's Hospital of Gansu Province,Lanzhou 730050,Gansu Province,China [4]Department of Respiratory Medicine,The 940th Hospital of Joint Logistic Support Force of the Chinese People's Liberation Army,Lanzhou 730050,Gansu Province,China

出　　处：《World Journal of Clinical Cases》2022年第30期11190-11197,共8页世界临床病例杂志

基　　金：Supported by Youth Science and Technology Foundation of Gansu Province,No.20JR5RA588;Youth Science and Technology Foundation of Gansu Province,No.21JR7RA014;Key RESEARCH and Development Program of Gansu Province,No.21YF5FA154。

摘　　要：BACKGROUND Fibrous hamartoma of infancy(FHI)is a rare disease of infancy with unknown etiology.The disease mainly involves soft tissue,has no specific clinical manifestations,and is difficult to diagnose.At present,the diagnosis is mainly confirmed by histopathological examination,and the main treatment is surgical resection of the pathological tissue,which is prone to recurrence.CASE SUMMARY A five-month-old female patient was admitted to our hospital with swelling in the right calf.Two biopsies were performed in our hospital and another hospital,respectively,confirming the diagnosis as fibrous hamartoma.After exclusion of surgical contraindications,resection was performed with clear margins of 1 cm.Radiographic examination showed tumor recurrence more than four months after the operation,and surgery was performed again to extend the resection margins to 1.5 cm.The patient is recovering well,and after a follow-up of 36 mo,shows no signs of recurrence.CONCLUSION Our case report demonstrates that FHI should be considered in the differential diagnosis for a lower extremity mass with bone destruction.For FHI with bone destruction and unclear boundaries,excision margins of 1.5 cm could be superior to margins of 1 cm.

关 键 词：INFANT TIBIA Fibrous hamartoma Bone destruction Case report 

分 类 号：R726.8[医药卫生—儿科] R730.5[医药卫生—临床医学]