血液标本质量对凝血指标检测结果的影响探究  

Effect of blood specimen quality on the test results of coagulation indexes

作　　者：杨立娜 YANG Li-na(Liaoyang Third People's Hospital,Liaoyang 111000,China)

机构地区：[1]辽阳市第三人民医院,111000

出　　处：《中国现代药物应用》2022年第18期86-88,共3页Chinese Journal of Modern Drug Application

摘　　要：目的 探究血液标本质量对凝血指标检测结果的影响。方法 对3000例进行凝血指标检验的患者的临床资料进行回顾性分析,检测其凝血指标[活化部分凝血活酶时间(APTT)、凝血酶时间(TT)、纤维蛋白原(FIB)、凝血酶原时间(PT)],比较凝血异常患者和凝血正常患者的凝血指标,并分析发生凝血异常的影响因素。结果 3000例患者中检出异常标本420例(14.00%),其中412例(13.73%)异常增高, 8例(0.27%)异常降低。凝血异常患者的PT(15.22±0.52)s、APTT(29.56±1.56)s、TT(16.92±0.82)s均长于凝血正常患者的(13.02±0.41)、(26.52±1.82)、(15.02±0.21)s, FIB(2.21±0.63)g/L低于凝血正常患者的(2.72±0.52)g/L,差异有统计学意义(P<0.05)。凝血异常患者血液标本采集量<3 ml占比、血液标本采集部位为末梢血占比、溶血标本占比、标本放置时间≥24 h占比分别为97.14%、28.57%、82.14%、75.24%,均高于凝血正常患者的2.60%、21.28%、0.31%、0.19%,差异有统计学意义(P<0.05)。经Logistic多因素回归分析显示:血液标本采集量、血液标本采集部位、溶血标本、标本放置时间等是凝血异常的独立危险因素(P<0.05)。结论 血液标本质量会对凝血指标检验结果产生影响,所以在进行血液标本采集中要严格的做好血液标本各个环节的工作,提升血液标本质量,确保凝血指标检验结果对患者病症的治疗提供可靠的依据。Objective To investigate the effect of blood specimen quality on the test results of coagulation indexes.Methods The clinical data of 3000 patients who underwent coagulation index tests were retrospectively analyzed for coagulation indexes[activated partial thromboplastin time(APTT),prothrombin time(TT),fibrinogen(FIB),and prothrombin time(PT)],and the coagulation indexes of patients with abnormal coagulation were compared with those of patients with normal coagulation,and the influencing factors were analyzed.Results Among the 3000 patients,420 cases(14.00%)were abnormal specimens,of which 412 cases(13.73%)were abnormally high and 8 cases(0.27%)were abnormally low.The PT(15.22±0.52)s,APTT(29.56±1.56)s and TT(16.92±0.82)s of the patients with abnormal coagulation were longer than(13.02±0.41),(26.52±1.82),(15.02±0.21)s of the patients with normal coagulation,and the FIB(2.21±0.63)g/L was lower than(2.72±0.52)g/L of the patients with normal coagulation,and the differences were statistically significant(P<0.05).The percentage of blood specimens collected<3 ml,the percentage of blood specimens collected from peripheral blood,the percentage of hemolyzed specimens,and the percentage of specimens storage for≥24 h of the patients with abnormal coagulation were 97.14%,28.57%,82.14%,and 75.24%,respectively,which were all higher than 2.60%,21.28%,0.31%,and 0.19%of patients with normal coagulation,and the differences were statistically significant(P<0.05).Logistic multivariate regression analysis showed that blood specimen collection volume,blood specimen collection site,hemolysis specimen,and specimen storage time were independent risk factors of abnormal coagulation(P<0.05).Conclusion The quality of blood specimen will have an impact on the results of coagulation index test.Therefore,before blood specimen collection,all aspects of blood specimens must be strictly done to improve the quality of blood specimens and ensure that the results of the coagulation index test provide a reliable basis for the treatment of p

关 键 词：凝血指标 血液标本质量 影响因素 标本采集量 标本采集部位 

分 类 号：R446.1[医药卫生—诊断学]