表观遗传修饰在过敏性鼻炎中的作用  

Role of epigenetic modification in allergic rhinitis

作　　者：李静 周义兵[1] 陈若希 邱昌余[2,3,4] 程雷 LI Jing;ZHOU Yi-bing;CHEN Ruo-xi;QIU Chang-yu;CHENG Lei(Department of Otorhinolaryngology,The Affiliated Jiangning Hospital of Nanjing Medical University,Nanjing 211100,China;Department of Otorhinolaryngology,The First Affiliated Hospital of Nanjing Medical University(Jiangsu Province Hospital),Nanjing 210029,China;Clinical Allergy Center,The First Affiliated Hospital of Nanjing Medical University(Jiangsu Province Hospital),Nanjing 210029,China;International Centre for Allergy Research,Nanjing Medical University,Nanjing 210029,China)

机构地区：[1]南京医科大学附属江宁医院耳鼻咽喉科,南京211100 [2]南京医科大学第一附属医院(江苏省人民医院)耳鼻咽喉科,南京210029 [3]南京医科大学第一附属医院(江苏省人民医院)过敏诊疗中心,南京210029 [4]南京医科大学国际变态反应研究中心,南京210029

出　　处：《中华临床免疫和变态反应杂志》2022年第3期261-266,共6页Chinese Journal of Allergy & Clinical Immunology

基　　金：国家自然科学基金(81800890,81970862)。

摘　　要：本文从DNA甲基化、组蛋白修饰及非编码RNA三个方面对近年来过敏性鼻炎的表观遗传修饰的研究进展作一综述。The recent advances in three pathways of epigenetic modification in allergic rhinitis,including DNA methylation,histone modification,and non-coding RNA were reviewed in this article.

关 键 词：过敏性鼻炎 表观遗传 DNA甲基化 组蛋白修饰 非编码RNA 

分 类 号：R765.21[医药卫生—耳鼻咽喉科]