干细胞治疗子宫内膜损伤的研究进展  

Research progress of stem cell therapy for endometrial injury

作　　者：王亚飞[1] 洪名云[1] 唐志霞[1] 李婉晴 WANG Yafei;HONG Mingyun;TANG Zhixia;LI Wanqing(Reproductive Medicine Center of Anhui Province Maternity and Child Health Hospital,Maternal and Child Health Care Hospital Affiliated to Anhui Medical University,Hefei,Anhui 230001,China)

机构地区：[1]安徽省妇幼保健院、安徽医科大学附属妇幼保健院生殖医学中心,安徽合肥230001

出　　处：《安徽医药》2022年第11期2153-2156,共4页Anhui Medical and Pharmaceutical Journal

基　　金：安徽省重点研究与开发计划项目(1704a0802171);合肥市借转补项目(J2018Y03)。

摘　　要：子宫内膜损伤在临床上分为宫腔粘连和薄型子宫内膜,常见原因是频繁的宫腔操作、感染、缺血等,主要表现为闭经、月经量减少,反复流产,不孕和胎盘异常等。常规的治疗手段效果较差。近年来,随着人们对干细胞研究的不断深入,利用干细胞修复受损子宫内膜成为一种新的选择。现简要综述子宫内膜损伤的机理及不同来源的干细胞修复子宫内膜损伤研究进展。Endometrial injury is clinically divided into intrauterine adhesions and thin endometrium.The common causes are frequent intrauterine operations,infections,ischemia,etc.The main manifestations are amenorrhea,decreased menstrual flow,repeated miscarriage,infertility and placental abnormalities.Conventional treatments are less effective.In recent years,with the deepening of stem cell research,the use of stem cells to repair damaged endometrium has become a new option.This paper briefly reviews the mechanism of endometrial injury and the research progress of stem cells from different sources to repair endometrial injury.

关 键 词：子宫内膜损伤 宫腔粘连 薄型子宫内膜 干细胞 

分 类 号：R711.74[医药卫生—妇产科学]