3-甲基环十五烯酮加氢合成麝香酮的研究  

Hydrogenation of 3-Methylcyclopentadecenone for the Synthesis of Musk Ketones

作　　者：高敏杰 杨宗美 游飞 王飞 Gao Minjie;Yang Zongmei;You Fei;Wang Fei(Guangdong Key Laboratory of Industrial Surfactant,Institute of Chemical Engineering Guangdong Academy of Sciences,Guangzhou 510665,China)

机构地区：[1]广东省工业表面活性剂重点实验室,广东省科学院化工研究所,广东广州510665

出　　处：《广东化工》2022年第20期4-7,37,共5页Guangdong Chemical Industry

基　　金：广东省科学院建设国内一流研究机构行动专项资金项目(2020GDASYL-20200503001-06);广东省科学院发展专项资金项目(2022GDASZH-2022010109)。

摘　　要：本文以3-甲基环十五烯酮为原料,在催化剂、加压、升温、搅拌等条件下,通入高纯氢气反应合成麝香酮。利用气相色谱仪、气质联用仪、红外光谱分析仪和核磁共振波谱仪等仪器进行检测,表征合成样品。采用单因素方法考查了3-甲基环十五烯酮催化加氢反应中催化剂种类、反应温度、反应压力、搅拌速度等对产率的影响。结果表明,以钯碳作为催化剂,反应压力2.0 MPa,反应温度90℃,搅拌速度为1100 rpm,反应时间为10 h的时候产率最高,达到89.3%。In this paper, muscone was synthesized by the reaction of 3-methyl cyclopentadecenone with high purity hydrogen under the conditions of catalyst,pressure, temperature and agitation. The samples were detected by GC, GC-MS, FTIR and NMR. The effects of catalyst type, reaction temperature, reaction pressure and stirring speed on the yield of catalytic hydrogenation of 3-methylcyclopentadienone were investigated by single factor method. The results showed that the highest yield was 89.3 % when palladium carbon was used as catalyst, the reaction pressure was 2.0 MPa, the reaction temperature was 90 ℃, the stirring speed was 1100 rpm, and the reaction time was 10 h.

关 键 词：麝香酮 加氢 钯碳 催化 3-甲基环十五烯酮 

分 类 号：TQ[化学工程]