可见光诱导4-色满酮合成:醋酸碘苯促进的α-酮酸与邻-烯丙氧基芳醛的自由基串联环化反应  

Visible Light-Induced 4-Chromanones Synthesis:Radical Cascade Cyclization ofα-Oxocarboxylic Acids with o-(Allyloxy)arylaldehydes Promoted by Phenyliodine(Ⅲ)Diacetate

作　　者：周旭煜 张爱君 张庆庆 刘庆安[1] 宣俊 Zhou Xuyu;Zhang Aijun;Zhang Qingqing;Liu Qing'an;Xuan Jun(Anhui Province Key Laboratory of Chemistry for Inorganic/Organic Hybrid Functionalized Materials,College of Chemistry&Chemical Engineering,Anhui University,Hefei 230601)

机构地区：[1]安徽大学化学化工学院无机-有机杂化功能材料化学安徽省重点实验室,合肥230601

出　　处：《有机化学》2022年第8期2488-2495,共8页Chinese Journal of Organic Chemistry

基　　金：Project supported by the National Natural Science Foundation of China(Nos.21971001,21702001);the National Undergraduate Training Program for Innovation and Entrepreneurship(No.202110357041)。

摘　　要：报道了在可见光照射下,通过醋酸碘苯(PIDA)促进的α-酮酸与邻-烯丙氧基芳醛的自由基串联环化反应,高效构建了含有1,4-二酮片段的4-色满酮衍生物.该反应在温和的条件下即可进行,如室温、蓝色LED灯照射、无需光氧化还原催化剂等.在最优的反应条件下,可以中等到好的产率得到目标杂环化合物.An efficient and sustainable visible light-promoted cascade radical cyclization ofα-oxocarboxylic acids with o-(allyloxy)arylaldehydes towards the construction of 1,4-diketone containing chromanone derivatives has been developed.The reaction occurred under mild reactions,e.g.room temperature,blue LED irradiation,photoredox catalyst free,and provided the final heterocycles in moderate to good yields.

关 键 词：可见光 4-色满酮 自由基 串联反应 

分 类 号：O626[理学—有机化学]