Effect of combined scalp and body acupuncture on Parkinson’s disease:A randomized clinical trial  

头针联合体针对帕金森病运动症状的治疗效应:随机临床研究

作　　者：Yuan-bin JIA Xiao-jun WANG Xing-ping LIU Peng WANG Chao DENG Zhong-zheng LI Ye ZHAO 贾元斌;王小军;刘兴平;王鹏;邓超;李中正;赵晔(泰国格乐大学国际学院公共卫生系,曼谷10200;吉首大学医学院,湖南吉首416000;吉首大学附属中医院,湖南吉首416000;吉首大学附属宁乡中医院,湖南长沙410600;山东中医药大学细胞行为组学研究中心,济南250355)

机构地区：[1]Department of Public Health,Krirk University,Bangkok 10200,Thailand [2]Jishou University School of Medicine,Jishou 416000,Hunan Province,China [3]Chinese Medicine Hospital Affiliated to Jishou University,Jishou 416000,Hunan Province,China [4]Ningxiang Hospital of Chinese Medicine Affiliated to Jishou University,Changsha 410600,Hunan Province,China [5]Research Center of Cytobehavioral Omics,Shandong University of Traditional Chinese Medicine,Jinan 250355,Shandong Province,China

出　　处：《World Journal of Acupuncture-Moxibustion》2022年第4期342-350,共9页世界针灸杂志（英文版）

基　　金：Supported by Funding Scientific Project of Education Division,Henan Province21C0374;Inheritance Studio of"Hunan Provincial Academic School of Five-Meridian Combined with Acupuncture and Tuina",State Administration of Traditional Chinese MedicineLP0118041。

摘　　要：Objective:To observe the therapeutic effect of combined scalp and body acupuncture on the motor symptoms in Parkinson’s disease(PD),and on the score of levodopa equivalent dose(LED).Methods:This is a randomized,single blind trial.Sixty-six patients with PD were randomized into an acupuncture+medication group(33 patients)and a medication group(33 patients).The patients were aware of allocation and the assessors were blinded to group assignment and therapeutic regimen.AntiPD drugs were administered in both groups.In the acupuncture+medication group,scalp and body acupuncture therapy was added.Treatments were applied for 8 weeks.In scalp acupuncture,the anterior oblique line of the vertex-temporal(MS6),lateral line 1 of the vertex(MS8),lateral line 2 of the vertex(MS9),and lower-lateral line of the occiput(MS14)were selected.In the body acupuncture,the acupoints included Bǎihuì(百会GV20),Sìshéncōng(四神聪EX-HN1),and Dàzhuī(大椎GV14),as well as the bilateral Fēngchí(风池GB20),Nèiguān(内关PC6),Hégǔ(合谷LI4),Gānshū(肝俞BL18),Shènshū(肾俞BL23),Yánglíngquán(阳陵泉GB34),Zúsānlǐ(足三里ST36),Fēnglóng(丰隆ST40),Sānyīnjiāo(三阴交SP6),Tàixī(太溪KI3),and Tàichōng(太冲LR3).Before and after treatments,the unified Parkinson’s disease rating scale(UPDRS),3section of the UPDRS(UPDRS-Ⅲ),and motor dysfunction rating scale for Parkinson’s disease(MDRSPD)were scored in the patients.The therapeutic effect of traditional Chinese medicine(TCM)and LED score were compared between both groups.Results:Thirty-three cases were included in data analysis in each group.After treatment,UPDRS scores were(28.77±8.85)and(36.58±10.16)points,UPDRS-Ⅲscores were(12.16±1.97)and(17.47±2.93)points and MDRSPD scores were(15.56±3.31)and(19.13±4.87)points in the acupuncture+medication and medication groups respectively.The UPDRS,UPDRS-Ⅲ,and MDRSPD scores all reduced after treatments in both groups(all P<0.05).All three scores were lower in the acupuncture+medication group than in t

关 键 词：Parkinson’s disease Motor symptoms Scalp acupuncture Body acupuncture Randomized controlled trial(RCT) Levodopa equivalent dose 

分 类 号：R246.6[医药卫生—针灸推拿学]