血清补体C1q水平对冠心病诊断价值的Meta分析  

Diagnostic value of serum complement C1q level in coronary heart disease:a Meta-analysis

作　　者：胡康 张开健 施展 张步春 HU Kang;ZHANG Kaijian;SHI Zhan;ZHANG Buchun(Graduate School of Wannan Medical College,Wuhu,Anhui 241000,China;Department of Cardiology,Anhui Provincial Hospital Affiliated to Anhui Medical University,Hefei,Anhui 230001,China;The First Affiliated Hospital of University of Science and Technology of China,Hefei,Anhui 230001,China)

机构地区：[1]皖南医学院研究生学院,安徽省芜湖市241000 [2]安徽医科大学附属省立医院心血管内科,安徽省合肥市230001 [3]中国科学技术大学附属第一医院心血管内科,安徽省合肥市230001

出　　处：《中国动脉硬化杂志》2022年第11期982-986,共5页Chinese Journal of Arteriosclerosis

基　　金：安徽省卫生健康委科研资助项目(AHWJ2021b082)。

摘　　要：[目的]分析血清补体C1q水平对冠心病的诊断价值。[方法]计算机检索中国知网、万方数据库、PubMed、Web of Science、Cochrane、Embase等数据库,搜集血清补体C1q水平对冠心病诊断价值的病例-对照研究,检索时间截至2021年9月。采用RevMan5.4和Stata16.0软件进行Meta分析。[结果]共有10篇文献符合纳入标准,研究对象共计2 011例,Meta分析结果显示血清补体C1q水平在冠心病组与对照组中的差异无统计学意义(SMD=-0.19,95%CI:-0.85~0.48,P=0.58)。[结论]血清补体C1q水平也许不能够作为冠心病诊断的一项指标。Aim To evaluate the diagnostic value of serum complement C1 q level in coronary heart disease. Methods Case-control studies on the diagnostic value of serum complement C1 q level in coronary heart disease were collected by computer retrieval from CNKI, Wanfang, PubMed, Web of Science, Cochrane, Embase and other databases until September 2021. Meta-analysis was performed using RevMan 5.4 and Stata16.0 software. Results A total of 10 literatures met the inclusion criteria, involving a total of 2 011 subjects. Meta-analysis showed that there was no significant difference in serum complement C1 q level between the coronary heart disease group and the control group(SMD=-0.19, 95%CI:-0.85~0.48,P=0.58). Conclusion Serum complement C1 q level may not be a diagnostic indicator of coronary heart disease.

关 键 词：冠心病 血清补体C1q META分析 

分 类 号：R514.4[医药卫生—内科学]