智能化患者自控镇痛用于术后镇痛的疗效和安全性meta分析  

Meta-analysis of the efficacy and safety of artificial intelligence patient-controlled analgesia for postoperative analgesia

作　　者：申金海 黄天文[1] 王琳玉 李艳[1] SHEN Jinhai;HUANG Tianwen;WANG Linyu;LI Yan(Department of Pharmacy,Guangxi Medical University Cancer Hospital,Guangxi Zhuang Autonomous Region,Nanning 530021,China.)

机构地区：[1]广西医科大学附属肿瘤医院药学部,广西南宁530021

出　　处：《中国当代医药》2022年第30期26-30,共5页China Modern Medicine

摘　　要：目的系统评价智能化患者自控镇痛用于术后镇痛的疗效和安全性。方法计算机检索PubMed、Embase、Cochrane Library、Web of Science、知网、维普、万方等数据库建库至2021年10月20日关于智能化患者自控镇痛对比患者自控镇痛用于术后镇痛的随机对照试验(RCT)。对文献进行筛选、质量评价和数据提取后,使用统计软件RevMan 5.4进行meta分析。结果共纳入17项RCT研究,共7746例患者,其中试验组4904例,对照组2842例。meta分析显示:试验组的术后24和48 h视觉模拟评分法(VAS)评分均显著低于对照组[MD=-0.47,95%CI(-0.75,-0.19),P=0.0010]、[MD=-0.42,95%CI(-0.65,-0.20),P=0.0003]。试验组的患者满意度显著高于对照组[RR=1.15,95%CI(1.13,1.18),P<0.00001]。试验组的不良反应总发生率显著低于对照组[RR=0.75,95%CI(0.67,0.84),P<0.00001]。而两组术后24和48 h疼痛数字评分比较,差异均无统计学意义(P>0.05)。结论智能化患者自控镇痛用于术后镇痛的疗效和安全性优于患者自控镇痛。Objective To systematically evaluate the efficacy and safety of artificial intelligence patient-controlled analgesia(AI-PCA)for postoperative analgesia.Methods Trials about AI-PCA versus patient-controlled analgesia(PCA)for postoperative analgesia published in PubMed,Embase,Cochrane Library,Web of Science,CNKI,VIP,Wanfang Databases from the inception to October 20,2021 were collected.After literature screening,quality assessment and data extraction,meta-analysis was conducted with RevMan5.4 software.Results A total of 17 RCTs were included,with a total of 7746 patients,including 4904 in the trial group and 2842 in the control group.The meta-analysis showed that the postoperative visual analogue scale(VAS)at 24 and 48 h of trial group was significantly less than that of control group(MD=-0.47,95%CI[-0.75,-0.19],P=0.0010),(MD=-0.42,95%CI[-0.65,-0.20],P=0.0003).The patient satisfaction of the trial group was significantly higher than that of the control group(RR=1.15,95%CI[1.13,1.18],P<0.00001).The overall incidence of adverse reactions of trial group was significantly lower than that of control group(RR=0.75,95%CI[0.67,0.84],P<0.00001).But there was no statistical significance of postoperative NRS at 24 and 48 h in two groups(P>0.05).Conclusion The efficacy and safety of the AI-PCA for postoperative analgesia are better than PCA.

关 键 词：智能 镇痛 疗效 安全性 META分析 

分 类 号：R619[医药卫生—外科学]