滋肾调冲汤治疗黄体功能不足性月经失调效果及对血清性激素水平的影响  

Effect of Zishen Tiaochong decoction on menstrual disorder with luteal insufficiency and influence on serum hormone level

作　　者：陈风华 雷爱珍 Chen Fenghua;Lei Aizhen(Department of Obstetrics and Gynecology,Feicheng Hospital of Traditional Chinese Medicine,Feicheng 271600,China;Department of Obstetrics and Gynecology,Wangzhuang Town Health Center,Feicheng 271600,China)

机构地区：[1]山东省肥城市中医医院妇产科,山东肥城271600 [2]山东省肥城市王庄镇卫生院妇产科,山东肥城271600

出　　处：《实用妇科内分泌电子杂志》2022年第12期62-65,共4页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的探讨滋肾调冲汤治疗黄体功能不足性月经失调效果及对血清性激素水平的影响。方法选取60例黄体功能不足性月经失调患者,按照随机数字表法分为对照组与研究组,每组30例。对照组使用常规西药治疗,研究组在对照组基础上使用滋肾调冲汤治疗。对比两组临床疗效、中医证候积分、各项临床评分及性激素水平。结果研究组治疗总有效率为96.67%,明显高于对照组的73.33%,差异有统计学意义(P<0.05)。研究组治疗后月经先后不定期(0.72±0.21)分、经量多或少(0.78±0.24)分、月经淋沥不畅(0.70±0.21)分、腰骶酸痛(0.67±0.18)分、经色暗质稀薄(0.73±0.21)分,均明显低于对照组的(1.43±0.27)、(1.51±0.26),(1.52±0.25)、(1.56±0.27)、(1.43±0.26)分,差异有统计学意义(P<0.05)。研究组治疗后高温相评分(HPS)评分(6.87±1.46)分明显高于对照组(5.69±1.90)分,月经症状评分(2.43±0.75)分明显低于对照组(3.98±0.92)分,黄体期基础体温(BBT)高温时间(13.57±1.28)d明显长于对照组(12.05±1.16)d,差异有统计学意义(P<0.05)。治疗前,两组雌二醇(E_(2))、孕酮(P)、垂体泌乳素(PRL)、促黄体生成素(LH)及卵泡刺激素(FSH)水平比较,差异无统计学意义(P>0.05);治疗后,研究组E_(2)、P、LH水平高于对照组,PRL水平低于对照组,差异有统计学意义(P<0.05),但两组FSH水平比较,差异无统计学意义(P>0.05)。结论滋肾调冲汤治疗黄体功能不足性月经失调效果显著,能有效恢复患者月经周期及经量,调整血清性激素水平,值得临床推广与应用。Objective To investigate the effect of Zishen Tiaochong decoction on menstrual disorders caused by luteal insufficiency and its influence on serum sex hormone levels.Methods 60 patients with menstrual disorders caused by luteal insufficiency were randomly divided into control group and study group,with 30 cases in each group.The control group was treated with conventional western medicine,while the study group was treated with Zishen Tiaochong decoction on the basis of the control group.The clinical efficacy,TCM syndrome scores,clinical scores and sex hormone levels were compared between the two groups.Results The total effective rate of the study group was 96.67%,significantly higher than that of the control group(73.33%),and the difference was statistically significant(P<0.05).After treatment,the study group had irregular menstruation(0.72±0.21)points,more or less menstruation(0.78±0.24)points,poor menstruation leaching(0.70±0.21)points,lumbosacral pain(0.67±0.18)points,and thin dark matter(0.73±0.21)points.The scores were significantly lower than those of the control group(1.43±0.27),(1.51±0.26),(1.52±0.25),(1.56±0.27),(1.43±0.26),and the differences were statistically significant(P<0.05).After treatment,the high temperature phase score(HPS)of the study group(6.87±1.46)was significantly higher than that of the control group(5.69±1.90),and the menstrual symptom score(2.43±0.75)was significantly lower than that of the control group(3.98±0.92).The high temperature time of basal body temperature(BBT)in the luteal phase(13.57±1.28)d was significantly longer than that in the control group(12.05±1.16)d,and the difference was statistically significant(P<0.05).Before treatment,there was no significant difference in the levels of estradiol(E_(2)),progesterone(P),pituitary prolactin(PRL),luteinizing honnone(LH)and follicle-stimulating hormone(FSH)between the two groups(P>0.05).After treatment,the levels of E_(2),P and LH in the study group were higher than those in the control group,and the levels of PRL

关 键 词：黄体功能不足性月经失调 滋肾调冲汤 临床效果 血清性激素 

分 类 号：R271.111[医药卫生—中医妇科学]