以离子液体为溶剂一锅法三组分合成螺环吡喃衍生物  

A facile synthesis of spiropyran derivatives via one-pot three component reaction in ionic liquid without any catalyst

作　　者：李聪豪 郭红云[1] LI Cong-hao;GUOHong-yun(College of Chemical Engineering,Zhejiang University of Technology,Hangzhou 310014,China)

机构地区：[1]浙江工业大学,浙江杭州310014

出　　处：《应用化工》2018年第S02期188-192,共5页Applied Chemical Industry

摘　　要：使用离子液体为溶剂,在不添加额外催化剂条件下,采用多组分(MCR)一锅法反应,以靛红(或茚三酮),丙二腈(或氰基乙酸乙酯)、1,3-二酮为原料,三组分反应合成了一系列螺环吡喃衍生物,所有产物经IR,^(1)H NMR,质谱进行了确定。该方法的优点在于后处理简单,产量高,环境污染小。A series of spiropyran derivatives were synthesized via three component reaction of isatin/ninhydrin,malononitrile/ethylcyanoacetate and 1,3-diketones in ionic liquid without any catalyst.All the products were identified by IR,^(1)H NMR and mass spectroscopy.The method provided several advantages such as easier work-up,high yields and environmentally benign procedure.

关 键 词：螺环吡喃衍生物 三组分反应 离子液体 一锅法 

分 类 号：TQ016.1[化学工程] O626.32[理学—有机化学]