穴位埋线联合生活方式干预治疗糖尿病前期30例临床观察  

Clinical Observation on Catgut Embedding at Acupoints and life Style Intervention for Treatment of Prediabetes

作　　者：杨丽霞[1] 李靖[1] 刘莹[1] 吴蒙 邱建文 赵晓华[1] YANG Lixia;LI Jing;LIU Ying;WU Meng;QIU Jianwen;ZHAO Xiaohua(Shenzhen Hospital of Guangzhou University of Chinese Medicine(Futian),Shenzhen 518034,China)

机构地区：[1]广州中医药大学深圳医院,广东深圳518034

出　　处：《中国民族民间医药》2022年第19期111-114,共4页Chinese Journal of Ethnomedicine and Ethnopharmacy

基　　金：2019年度深圳市福田区卫生公益性科研项目(FTWS2019023);2020年广东省中医药管理局中医药科研项目(20201313);深圳市中医重点学科建设经费资助(ZYTS019)。

摘　　要：目的:观察穴位埋线干预糖尿病前期的有效性、安全性及对胃肠激素调节的影响。方法:选择符合糖尿病前期的60名受试者,按照随机对照试验方法分为观察组和对照组各30例,对照组给予生活方式干预;观察组在生活方式干预的基础上配合穴位埋线治疗,15 d穴位埋线1次,共完成6次穴位埋线。对比两组治疗前后空腹血糖(FPG)、餐后2 h血糖(2hPG)、空腹胰岛素(FINS)、糖化血红蛋白(HbA1c)、生长激素释放肽(Ghrelin)水平,观察并记录观察组治疗期间发生的不良反应。结果:两组治疗后FBG、 2hPG、 FINS、 HbA1c均有下降,且观察组明显低于对照组(P<0.05);两组治疗后Ghrelin水平较治疗前升高,且观察组较对照组明显;观察埋线后发生六种术后反应,包括饮食抑制、全身肌肉酸痛和局部疼痛、血肿和淤青,均未发生发热和局部感染情况。结论:穴位埋线干预糖尿病前期效果明显,可有效降低血糖相关生化指标,这可能是与调节体内生长激素释放肽水平有关,且无明显不良反应,值得临床研究和应用。Objective To observe the effect and safety of acupoint catgut embedding for prediabetes.Methods Sixty patients with prediabetes were randomly assigned into an observation group and a control group, 30 cases in each one. Diabetes health education and life-style intervention were applied in the two groups. Catgut embedding was used in the observation group, once every 15 days for 6times. Fasting plasma glucose(FPG), 2 hours postprandial blood glucose(2 hPG), fasting serum insulin(FINS) and glycosylated hemoglobin(HbA1c) were tested before and after treatment. The clinical efficacy was evaluated. The type and number of postoperative reactions had been recorded during the treatment.Results After treatment, the levels of FPG, 2hPG, FINS, HbA1c of the observation group were lower than those before treatment and those of the control group(P< 0. 05). After treatment, the level of Ghrelin in the observation group was higher than that before treatment and that in the control group(P< 0. 05). Six postoperative reactions occurred after embedding, including dietary inhibition, muscular ache and local discomfort, such as pain, hematoma and bruise. No fever and local infection occurred.Conclusion Catgut embedding can effectively reduce blood sugar related indexes, may be related to regulating the level of Ghelin, and no obvious adverse reactions.

关 键 词：穴位埋线 糖尿病前期 生长激素释放肽 

分 类 号：R587.1[医药卫生—内分泌]