枸杞化学成分及其药理作用研究  

Research on active components of Lycium chinense and their pharmacological effects

作　　者：邹新 产柳佳 易冰 丁世磊 裴栋[3] 魏鉴滕 赵立春 ZOU Xin;CHAN Liu-jia;YI Bing;DING Shi-lei;PEI Dong;WEI Jian-teng;ZHAO Li-chun(Guangxi University of Chinese Medicine,Nanning 530200,China;Guangxi Zhuang Yao Medicine Center of Engineering and Technology,Nanning 530200,China;Key Laboratory of Chemistry of Northwestern Plant Resources/Lanzhou Institute of Chemical Physics,Chinese Academy of Sciences,Lanzhou 730000,China)

机构地区：[1]广西中医药大学药学院,南宁530200 [2]广西壮瑶药工程技术研究中心,南宁530200 [3]中国科学院兰州化学物理研究所/中国科学院西北特色植物资源化学重点实验室,兰州730000

出　　处：《湖北农业科学》2022年第18期120-130,共11页Hubei Agricultural Sciences

基　　金：国家自然科学基金项目(81860691);国家“青年岐黄学者”人才项目;广西自然科学基金项目(2020GXNSFAA238021);广西一流学科开放课题(2019XK104);广西高等学校高水平创新团队资助项目(2019-52);。

摘　　要：随着对传统中药枸杞(Lycium chinense)研究的不断深入,发现其化学成分丰富多样,含有生物碱类、多糖类、黄酮类、苯丙素类及其他类化学成分。枸杞的药理作用研究也在不断扩展,拥有保护肝肾、抗氧化、抗衰老、抗肿瘤、神经保护活性、抗炎、退热、降血糖及其他药理作用等。对枸杞和宁夏枸杞的化学成分及其药理作用研究进展进行了综述,为枸杞价值挖掘、资源开发进一步扩展提供参考。With the continuous deepening of the research on the traditional Chinese medicine Lycium chinense,it is found that its chemical components are rich and diverse,including alkaloids,polysaccharides,flavonoids,phenylpropanoids and so on.Lycium chi⁃nense has a variety of pharmacological activities such as liver and kidney protection,anti-oxidation,anti-aging,anti-tumor,neuro⁃protective activity,anti-inflammatory,antipyretic,hypoglycemic and so on,and its pharmacological effect research is also expand⁃ing.In this paper,the chemical constituents and pharmacological effects of Lycium chinense and Lycium barbarum are reviewed,which can provide reference for the value excavation and resource development of Lycium chinense.

关 键 词：枸杞(Lycium chinense) 化学成分 药理作用 

分 类 号：R282[医药卫生—中药学]