冠心病患者PCI术后药物治疗依从性降低的危险因素  

Risk factors for decreased medication compliance in patients with coronary heart disease after PCI

作　　者：李敏[1] 郝平[1] 归方 归承莹[1] 吴佳雯 张雯 陈晓丽 LI Min;HAO Ping;GUI Fang;GUI Cheng-ying;WU Jia-wen;ZHANG Wen;CHEN Xiao-li(Department of Cardiology,Affiliated Putuo Hospital of Shanghai University of Traditional Chinese Medicine,Shanghai,200062,China)

机构地区：[1]上海中医药大学附属普陀医院心内科,上海200062

出　　处：《心血管康复医学杂志》2022年第5期566-570,共5页Chinese Journal of Cardiovascular Rehabilitation Medicine

基　　金：2020年度普陀区公共卫生重点学科和专项课题(ptgw202004)。

摘　　要：目的:研究冠心病患者经皮冠状动脉介入治疗(PCI)术后药物治疗依从性降低的危险因素。方法:依据高血压服药依从性(Mofisky-Green)测评表评分,于我院行PCI术的300例冠心病患者被分为依从性差组(163例,Mofisky-Green测评表评分≤6分)和依从性良好组(137例,Mofisky-Green测评表评分≥7分)。比较两组一般临床资料,分析冠心病患者PCI术后服抗血小板药物依从性评分的影响因素及其与依从性评分的相关性。结果:与依从性良好组比较,依从性差组女性、年龄61~71岁、无配偶、月收入<2000元、吸烟、糖尿病、无药物认知比例均显著升高(P均<0.01)。多因素Logistic回归分析显示,年龄61~71岁、无配偶、月收入<2000元、糖尿病、吸烟、无药物认知是冠心病患者PCI术后服抗血小板药物依从性评分的独立危险因素(OR=4.452~335.601,P<0.05或<0.01)。Spearman相关性分析显示,年龄61~71岁、无药物认知、无配偶、月收入<2000元、糖尿病及吸烟均与冠心病患者PCI术后服抗血小板药物依从性评分呈显著负相关(r=-0.416~-0.899,P均=0.001)。结论:年龄、婚姻状况、收入、吸烟、糖尿病、服药认知情况是影响冠心病患者PCI术后服抗血小板药物依从性降低的危险因素。Objective:To study risk factors for decreased medication compliance in patients with coronary heart disease(CHD)after percutaneous coronary intervention(PCI).Methods:According to score of drug compliance for hypertension(Mofisky-Green)scale,a total of 300 CHD patients undergoing PCI in our hospital were divided into poor compliance group(n=163,Mofisky-Green scale score≤6 scores)and good compliance group(n=137,Mofisky-Green scale score≥7 scores).General clinical data were compared between two groups,and influencing factors of antiplatelet drug compliance score after PCI in CHD patients and correlation between influencing factors and compliance score was analyzed.Results:Compared with good compliance group,there were significant rise in percentages of female,age 61~71 years,no spouse,monthly income<2000 RMB,smoking,diabetes mellitus(DM)and no drug awareness in poor compliance group(P<0.01 all).Multivariate Logistic regression analysis indicated that age 61~71 years,no spouse,monthly income<2000 RMB,smoking,DM and no drug awareness were independent risk factors for antiplatelet drug compliance score after PCI in CHD patients(OR=4.452~335.601,P<0.05 or<0.01).Spearman correlation analysis indicated that age 61~71 years,no spouse,monthly income<2000 RMB,smoking,DM and no drug awareness were significant inversely correlated with antiplatelet drug compliance score after PCI in CHD patients(r=-0.416~-0.899,P=0.001 all).Conclusion:Age,marital status,income,smoking,diabetes mellitus and medication awareness are risk factors for antiplatelet drug compliance reduce in CHD patients after PCI.

关 键 词：冠心病 血管成形术 气囊 冠状动脉 抗血小板聚集剂 

分 类 号：R541.4[医药卫生—心血管疾病]