肌少症与糖尿病心血管病变关系研究的进展  

Research progress on the relationship between sarcopenia and diabetic cardiovascular disease

作　　者：马勇鹏 李鹏杰[1] 王驰[1] 项莹[1] MA Yong-peng;LI Peng-jie;WANG Chi;XIANG Ying(Department of Endocrinology,Second Affiliated Hospital of Harbin Medical University,Harbin,Heilongjiang,150081,China)

机构地区：[1]哈尔滨医科大学附属第二医院内分泌科,黑龙江哈尔滨150081

出　　处：《心血管康复医学杂志》2022年第5期649-653,共5页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：心血管疾病是2型糖尿病患者死亡的主要原因。研究表明,和普通患者相比,糖尿病患者肌肉质量降低更加严重。肌少症会引起体内一系列变化,其中包括内皮细胞的炎症反应和糖、脂代谢的异常,后两者为导致糖尿病心血管病变的主要病理学基础。本文就肌少症与糖尿病心血管病变的关系与影响机制做一综述。Cardiovascular disease is a leading cause of death in patients with type 2 diabetes mellitus.Studies have indicated that people with diabetes mellitus(DM)have more severe loss of muscle mass compared with general patients.Sarcopenia can cause a series of changes in body,including inflammatory response of endothelial cells and abnormal glucose and lipid metabolism,and the latter two being main pathological basis of diabetic cardiovascular disease.The present article makes a review on relationship between sarcopenia and diabetic cardiovascular disease and its influencing mechanism.

关 键 词：心血管疾病 糖尿病 2型 肌疾病 

分 类 号：R54[医药卫生—心血管疾病]