益肾解毒法治疗慢性肾脏病机制研究进展  

Research progress on the mechanism of treating chronic kidney disease by invigorating the kidney and removing toxic

作　　者：康蕾蕾 周恩超[2] KANG Lei-lei;ZHOU En-chao(Affiliated Hospital of Nanjing University of Traditional Chinese Medicine,Nanjing 210029,China;Jiangsu Hospital of Traditional Chinese Medicine,Nanjing 210029,China)

机构地区：[1]南京中医药大学附属医院,江苏南京210029 [2]江苏省中医院,江苏南京210029

出　　处：《海南医学院学报》2022年第20期1595-1600,共6页Journal of Hainan Medical University

基　　金：国家自然科学基金(81873270);江苏省“六大人才高峰”高层次人才项目(WSN-012);南京市科技局医疗卫生国际联合研发项目(202002051);南京中医药大学中医学优势学科三期项目(ZYX03KF076);江苏省中医院“高峰学术”人才项目(y2018rc17)。

摘　　要：慢性肾脏病是各种肾脏病的总称,有病程长、早期难以发现等特点,是当今亟待解决的社会性疾病之一,其发病机制和治疗一直是研究的热点和难点,研究表明中医药是延缓慢性肾脏病进展的有效措施。根据国家级名中医临床经验,慢性肾脏病可依据其“肾虚为本、毒邪为标”的病机,采用益肾解毒法治疗。基于上述背景,本文概述了现代研究中益肾解毒类中药汤剂从多机制、多通路等延缓慢性肾脏病的研究进展。Chronic kidney disease is a general term for various types of renal diseases characterized by a long course of dis⁃ease and difficulty in early detection.It is one of the social diseases that need to be solved urgently and its pathogenesis and treat⁃ment have always been a hotspot for researchers.Studies have shown that traditional Chinese medicine(TCM)can effectively de⁃lay the progress of chronic kidney disease.According to the clinical experience of national famous TCM physicians,based on its pathogenesis of"kidney deficiency as the foundation and poison as the target",chronic kidney disease can be treated by invigorating the kidney and removing toxic.Based on the above background,this paper summarizes the research progress of invigorating the kidney and removing toxic in delaying chronic kidney disease from multiple mechanisms and pathways in modern research.

关 键 词：慢性肾脏病 益肾解毒法 研究进展 

分 类 号：R277.5[医药卫生—中医学]