超声SWE、SWD技术在代谢功能障碍相关性脂肪肝病中的初步研究  

A Preliminary Study on Ultrasonic Shear Wave Elastrography and Shear Wave Dispersion Technique in Metabolism-related Fatty Liver Disease

作　　者：李亚雪 薛红元[1] 武晓静[1] 高强 许栩 Li Yaxue;Xue Hongyuan;Wu Xiaojing;Gao Qiang;Xu Xu(Department of Ultrasound,Hebei General Hospital,Shijiazhuang 050000,China;Department of Service,Beijing Corps Hospital of PAP,Beijing 100027,China)

机构地区：[1]河北省人民医院超声科,石家庄市050000 [2]武警北京市总队医院卫勤处,北京市100027

出　　处：《中国超声医学杂志》2022年第10期1128-1131,共4页Chinese Journal of Ultrasound in Medicine

摘　　要：目的 探究超声剪切波弹性成像(SWE)和剪切波频散成像(SWD)技术诊断代谢功能障碍相关性脂肪肝病(MAFLD)的应用价值,以及正常人群的测量参考值。方法 使用常规超声和SWE、SWD技术对255例研究对象进行肝脂肪变性检测。以常规超声为参考标准,应用ROC曲线评估SWE、SWD技术诊断脂肪肝的效能。分析SWE值、SWD值与脂肪肝程度相关性。结果 对照组平均SWE值、SWD值分别为(1.41±0.13)m/s、(12.94±1.16)m/s·kHz。MAFLD组SWE值、SWD值显著高于对照组(P<0.05)。不同程度MAFLD组SWD值差异有统计学意义(P<0.05),SWD值与脂肪肝程度呈正相关(r=0.852,P<0.001);SWE与脂肪肝程度呈正相关(r=0.604,P<0.001),但中、重组之间无差异。SWE、SWD值对不同程度脂肪肝有较好的诊断效能,ROC曲线下面积为0.791~0.992。结论 SWE、SWD技术在正常人群中获得参数值为临床评估提供参考,对MAFLD及程度有较高的诊断效能,是定量检测MAFLD的可靠工具。Objective To explore the application value of shear wave elastrography and shear Wave dispersion imaging in the diagnosis of metabolic dysfunction-related fatty liver disease, and to define the reference value in the normal population. Methods Conventional ultrasound, SWE and SWD were used to detect hepatic steatosis in 255 subjects. Using ultrasound as the reference standard, ROC curve was used to evaluate the efficacy of the techniques in diagnosing fatty liver, and the correlation between the technique and the grade of liver steatosis was analyzed. Results The mean SWE and SWD values of the normal population were(1.41±0.13)m/s and(12.94±1.16)m/s·kHz, respectively. The SWE and SWD values in MAFLD group were significantly higher than those in control group(P<0.001).There was significant difference in SWD value between groups(P<0.05), SWD value was positively correlated with the degree of MAFLD(r=0.852, P<0.001).There was a positive correlation between SWE value and the degree of MAFLD(r=0.604,P<0.001), but there was no statistical difference between moderate and severe groups. The area under ROC curves for SWE, SWD were better(0.791~0.992). Conclusions SWE and SWD techniques can obtain parameter values in the normal population and provide reference for clinical evaluation. They have high diagnostic efficacy for MAFLD and its severity, and are reliable tools for quantitative detection of MAFLD.

关 键 词：剪切波弹性成像 剪切波频散成像 代谢功能障碍相关性脂肪肝病 

分 类 号：R445.1[医药卫生—影像医学与核医学] R575.5[医药卫生—诊断学]