针刺蝶腭神经节联合嗅觉训练治疗上呼吸道感染后嗅觉障碍临床研究  

Clinical Study of Sphenopalatine Ganglion Acupuncture Combined with Olfactory Training for Treatment of Dysosmia after Upper Respiratory Tract Infection

作　　者：李金飞[1] 丁雷[1] 王嘉玺[1] LI Jinfei;DING Lei;WANG Jiaxi(Dongfang Hospital,Beijing University of Chinese Medicine,Beijing 100078,China)

机构地区：[1]北京中医药大学东方医院,北京100078

出　　处：《中国中医药信息杂志》2022年第11期120-124,共5页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：北京中医药大学东方医院“1166”人才工程(030903010304)。

摘　　要：目的观察针刺蝶腭神经节联合嗅觉训练治疗上呼吸道感染后嗅觉障碍的疗效及其对嗅球体积的影响。方法采用随机数字表法将80例上呼吸道感染后嗅觉障碍患者分为观察组和对照组各40例。对照组予甲钴胺片,0.5 mg/次,3次/d,口服;糠酸莫米松鼻喷雾剂喷鼻,50μg/喷,每侧鼻孔2喷,1次/d。观察组采用针刺蝶腭神经节联合嗅觉训练疗法。2组均连续治疗12周。观察2组临床疗效,比较2组治疗前后嗅球体积变化,对2组进行安全性监测。结果治疗过程中观察组、对照组分别脱落4、5例。观察组总有效率为75.00%(27/36),对照组为42.86%(15/35),2组比较差异有统计学意义(P<0.05)。与本组治疗前比较,2组治疗后嗅球体积明显增大(P<0.05);2组治疗后比较,观察组嗅球体积大于对照组(P<0.05)。按疗效将患者分为有效组和无效组,与本组治疗前比较,有效组治疗后嗅球体积明显增大(P<0.05),无效组嗅球体积变化不明显(P>0.05);2组治疗后嗅球体积比较差异有统计学意义(P<0.05)。2组治疗期间生命体征、血常规、尿常规、肝功能、肾功能指标未见异常。结论针刺蝶腭神经节联合嗅觉训练可有效治疗上呼吸道感染后嗅觉障碍,并可显著增加患者嗅球体积。Objective To observe the effects of sphenopalatine ganglion acupuncture combined with olfactory training on dysosmia after upper respiratory tract infection;To explore its influence on the volume of olfactory bulb.Methods Totally 80 patients with olfaction after upper respiratory tract infection were divided into observation group(40 cases)and control group(40 cases).The control group was given mecobalamin tablets orally,0.5 mg/time,3 times/day,orally,and mometasone furoate nasal spray,50μg/time,twice/day in each side nostril.The observation group was treated with sphenopalatine ganglion acupuncture combined with olfactory training.Treatment for both groups lasted for 12 weeks.The clinical efficacy of 2 groups was observed.The changes of olfactory bulb volume in 2 groups before and after treatment were compared.Both groups were under safety monitoring.Results During the treatment,the observation group and the control group dropped out 4 and 5 cases,respectively.The total effective rate was 75.00%(27/36)in the observation group and 42.86%(15/35)in the control group,with statistical significance(P<0.05).Compared with before treatment,the volume of olfactory bulbs in the two groups increased significantly(P<0.05).After treatment,the volume of the olfactory bulb in the observation group increased more significantly(P<0.05).The patients were divided into the effective group and the ineffective group according to the efficacy Compared with before treatment,the volume of the olfactory bulb in the effective group increased significantly after treatment(P<0.05),while the volume of the olfactory bulb in the ineffective group did not change significantly(P>0.05);there was a statistically significant difference in the volume of the olfactory bulb between the two groups after treatment(P<0.05).No abnormality was found in the vital signs,blood routine,urine routine,liver function and renal function indexes in the two groups during treatment.Conclusion Sphenopalatine ganglion acupuncture combined with olfactory training can ef

关 键 词：嗅觉障碍 蝶腭神经节 嗅觉训练 上呼吸道感染 嗅球 临床研究 

分 类 号：R276.5[医药卫生—中医五官科学]