扫描式质子放疗系统自动化束斑测量与分析方法的设计和应用  

Design and application of automated spot measurement and analysis method for scanning proton radiation therapy system

作　　者：刘志鹏 单超 潘灵婧 王宇翔 王远远[1] 卢晓明 LIU Zhipeng;SHAN Chao;PAN Lingjing;WANG Yuxiang;WANG Yuanyuan;LU HsiaoMing(Hefei Ion Medical Center,the First Affiliated Hospital of University of Science and Technology of China,Hefei 230088,China;Ion Medical Research Institute,University of Science and Technology of China,Hefei 230088,China)

机构地区：[1]中国科学技术大学附属第一医院离子医学中心(合肥离子医学中心),安徽合肥230088 [2]中国科学技术大学离子医学研究所,安徽合肥230088

出　　处：《中国医学物理学杂志》2022年第10期1217-1224,共8页Chinese Journal of Medical Physics

摘　　要：目的:针对具有录像功能的闪烁体探测器Lynx-PT和笔形束扫描(PBS)质子放疗系统,设计一种质子束斑测量与分析方法,为PBS质子放疗系统的临床调试、束流建模和周期性质控测量提供可靠、高效的解决方案。方法:配置PBS质子放疗系统和Lynx-PT的相关参数,设计数据预处理和束斑分析流程,将两种数据处理流程嵌入自研软件(SpotCheck),实现从束斑采集到数据预处理再到束斑特性分析的全流程自动化。结果:SpotCheck输出的束斑尺寸结果与现有商业化软件(myQA,比利时IBA公司)以及厂商的现场验收测量结果均保持一致,能成功识别所有束斑录像文件的数据质量问题,并将质子束流占用时间从4 d缩短至0.5 d。结论:本文方法的束斑尺寸计算结果准确、束斑采集速度快、数据处理流程自动化程度高,极大提升了PBS质子放疗系统临床调试和束流建模的效率。Objective To design a method for automated proton spot measurement and analysis based on video scintillation detector Lynx-PT and pencil beam scanning(PBS) proton radiation therapy system, which can offer a reliable and efficient solution for PBS proton radiation therapy system commissioning, beam modeling, and routine quality assurance measurements. Methods Configuration items of PBS proton radiation therapy system and Lynx-PT were set up based on the spot acquisition requirements, and a data preprocessing workflow and a spot analysis workflow were designed and embedded in the self-developed software(SpotCheck) to realize the automation of spot acquisition, data preprocessing and spot analysis. Results The spot sizes calculated by SpotCheck were consistent with the results from a commercial software package(myQA, IBA, Belgium) and manufacturer’s on-site acceptance data. By SpotCheck, all the video data quality events were successfully recognized, and the measurement duration was significantly reduced from 4 days to 0.5 day. Conclusion The proposed method can provide accurate spot sizes, rapid spot acquisition and highly automated data processing, greatly improving the quality and efficiency of clinical commissioning and beam modeling.

关 键 词：质子放疗 笔形束扫描 临床调试 束斑分析 Lynx-PT 

分 类 号：R318[医药卫生—生物医学工程] TP317.4[医药卫生—基础医学]