磁共振功能成像在鉴别脑胶质瘤术后复发与放射性损伤中的应用分析  

Application Analysis of Functional Magnetic Resonance Imaging in Distinguishing Postoperative Recurrence and Radiation Injury of Glioma

作　　者：孙晓琳[1] SUN Xiao-lin(Department of Radiology,Central Hospital of Shenyang Medical College,Liaoning Shenyang 110000)

机构地区：[1]沈阳医学院附属中心医院放射科,辽宁沈阳110000

出　　处：《中国医疗器械信息》2022年第17期67-69,共3页China Medical Device Information

摘　　要：目的:分析鉴别脑胶质瘤术后复发和放射性损伤时应用功能磁共振成像效果。方法:选择2017年9月~2018年9月18例脑胶质瘤术后复发患者为复发组,20例脑胶质瘤放射性损伤患者为损伤组,均接受灌注加权成像、1H-磁共振波谱成像(1H-Magnetic Resonance Spectroscopy,1H-MRS)及弥散加权成像,析检查结果。结果:复发组平均标准化脑血容量为(4.01±0.62)优于损伤组的(1.36±0.36),t=16.3155,P=0.0000;复发组最大标准化CBV(3.35±0.55)高于损伤组的(1.19±0.33),t=14.8541,P=0.0000;复发组表观弥散系数、胆碱/肌酸、N-乙酰天门冬氨酸/胆碱与损伤组数据相近,无统计学意义,P>0.05。结论:选择功能磁共振成像鉴别脑胶质瘤的术后复发和放射性损伤有意义,1H-磁共振波谱成像和扩散加权成像只起辅助作用,不能直接作为诊断标准。Objective:To analyze the effect of functional magnetic resonance imaging(fMRI)in the identification of postoperative recurrence and radiation injury of glioma.Methods:From September 2017 to September 2018,18 patients with glioma recurrence after surgery were in the recurrence group,and 20 patients with glioma radiation injury were in the injury group.All of them underwent magnetic resonance imaging(PWI),1H-Magnetic Resonance Spectroscopy Imaging(1H-MRS)and Diffusion Formaldehyde Imaging(DWI),analyze the inspection results.Results:The average normalized cerebral blood volume(CBVnorm)(4.01±0.62)of the recurrence group was better than that of the injury group(1.36±0.36)(t=16.3155,P=0.0000);The maximum CBVnorm(3.35±0.55)of the recurrence group was higher than that of the injury group(1.19±0.33)(t=14.8541,P=0.0000);ADC,Cho/Cr,Cho/NAA in the recurrence group were similar to those in the injury group,and there was no statistical significance(P>0.05).Conclusion:It is meaningful to choose fMRI to distinguish postoperative recurrence and radiation damage of glioma.1H-magnetic resonance spectroscopy imaging and diffusion formaldehyde imaging only play an auxiliary role and cannot be directly used as diagnostic criteria.

关 键 词：磁共振功能成像 脑胶质瘤 术后复发 放射性损伤 

分 类 号：R445.2[医药卫生—影像医学与核医学]