药物涂层球囊对老年冠心病的治疗效果及对主支最小管腔直径、靶病变血运重建的影响分析  

Therapeutic Effect of DCB on Senile Coronary Heart Disease and Its Influence on the Minimum Lumen Diameter of Main Branch and Revascularization of Target Lesion

作　　者：鲁玮 孟亮[1] 陈曦 李敬[1] LU Wei;MENG Liang;CHEN Xi;LI Jing(Department of Cardiovascular Medicine,Affiliated Central Hospital of Shenyang Medical College,Liaoning Shenyang 110024)

机构地区：[1]沈阳医学院附属中心医院心血管内科,辽宁沈阳110024

出　　处：《中国医疗器械信息》2022年第17期125-127,共3页China Medical Device Information

摘　　要：目的:分析讨论在老年冠心病的治疗中,药物涂层球囊(Drug-Coated Balloon,DCB)技术对主支最小管腔直径及靶病变血运重建的临床疗效。方法:使用简单随机抽样法,从2018年7月~2020年7月于本院治疗的老年冠心病患者中抽取48例,并以随机抽签法进行分组。分组完成后,对照组内患者采用药物洗脱支架进行治疗,观察组内患者则选择DCB的治疗方案,在治疗后对两组患者的治疗效果进行评价,包括靶病变血运重建及再狭窄发生率、主支最小管腔直径、心脏不良事件发生率、心功能指标。结果:观察组患者治疗后最小管腔直径大于对照组,且观察组患者靶病变血运重建率更低,而对照组患者的心脏不良事件发生率及再狭窄发生率更高,观察组LVEF、SV水平均高于对照组,NT-proBNP水平低于对照组(P<0.05)。结论:DCB在老年冠心病的治疗中具有更好的治疗效果,不仅操作方便且治疗安全性更高、不易复发。Objective:To analyze and discuss the clinical effect of drug-coated balloon(DCB)technique on the minimum lumen diameter of main branch and the revascularization of target lesion in the treatment of senile coronary heart disease.Methods:Using the simple random sampling method,48 elderly patients with coronary heart disease who were treated in our hospital from July 2018 to July 2020 were selected and randomly divided into groups.After the grouping was completed,the patients in the control group were treated with drug-eluting stents,and the patients in the observation group were treated with DCB.After treatment,the therapeutic effects of the two groups of patients were evaluated,including the incidence of target lesion revascularization and restenosis,the smallest lumen diameter of the main branch,the incidence of adverse cardiac events,and cardiac function indicators.Results:After treatment,the minimum lumen diameter of the observation group was larger than that of the control group,and the target lesion revascularization rate of the observation group was lower,while the incidence of cardiac adverse events and restenosis of the control group was higher.The level of SV was higher than that of the control group,and the level of NT-proBNP was lower than that of the control group(P<0.05).Conclusion:Drug-coated balloon has better therapeutic effect in the treatment of senile coronary heart disease,which is not only easy to operate,but also has higher treatment safety and is not easy to relapse.

关 键 词：药物涂层球囊 老年冠心病 靶病变血运重建 主支最小管腔直径 

分 类 号：R541.4[医药卫生—心血管疾病]